Category Indole based

ADBICA

Summary ADBICA, also known as ADB-PICA, surfaced as a designer drug within synthetic cannabis blends in Japan back in 2013. Notably, before its inclusion as a component of synthetic cannabis blends, ADBICA had remained absent from scientific literature. This compound…

ADB-FUBICA

Summary ADB-FUBICA is a pharmaceutical compound that exerts substantial agonistic effects on cannabinoid receptors, displaying EC50 values of 2.6 nM at CB1 and 3.0 nM at CB2. Identifiers IUPAC name CAS Number 1801338-23-7  UNII S3ABP24K72 Chemical and physical data Formula…

ADB-FUBIATA

Summary ADB-FUBIATA, also known as AD-18 or FUB-ACADB, emerged as a synthetic cannabinoid compound in 2021. It shares structural similarities with the older combination ADB-FUBICA, with a notable distinction – an extended amide linker group by adding a methylene bridge.…

AB-PICA

Summary AB-PICA exhibits significant potency as an agonist for both the CB1 receptor (with an EC50 of 12 nM) and the CB2 receptor (also with an EC50 of 12 nM). Identifiers IUPAC name CAS Number 1801338-24-8 1445583-48-1 (racemate) UNII BWQ0BJ2OGXQ71G788A6H  Chemical…

AB-FUBICA

Summary AB-FUBICA is a compound that is a potent agonist for cannabinoid receptors, displaying notable EC50 values of 21 nM at CB1 and 15 nM at CB2. Identifiers IUPAC name CAS Number 1801338-22-6  ChemSpider 57427397 UNII U6SUE53VVY Chemical and physical…

AB-005

Summary AB-005, also known as 1-[(1-methylpiperidin-2-yl)methyl]-1H-indol-3-yl-methanone, is a designer drug offered by online vendors, positioned as a cannabimimetic agent. This compound’s structure and pharmacological activity were first documented in 2010, well before its availability in the commercial market in 2012. Studies…

5F-SDB-006

Summary 5F-SDB-006 is a substance known to function as a potent agonist for cannabinoid receptors. It exhibits an EC50 of 50 nM for human CB1 receptors and 123 nM for human CB2 receptors. This compound was first identified during investigations…

5F-NNE1

Summary 5F-NNE1, also recognized by its aliases 5F-NNEI and 5F-MN-24, represents an indole-derived synthetic cannabinoid. This compound is believed to act as a robust agonist of the CB1 receptor and has been made available for purchase on online platforms as…

MMB-2201

Summary MMB-2201, known by various aliases such as 5F-MMB-PICA, 5F-AMB-PICA, and I-AMB, is a potent synthetic cannabinoid founded on the indole-3-carboxamide structure. This compound has gained notoriety for its presence in the designer drug market and its use as an…

5F-ADBICA

Summary 5F-ADBICA, also referred to as 5F-ADB-PICA, is an indole-derived synthetic cannabinoid recognized for its agonistic solid activity at both CB1 and CB2 receptors, displaying remarkable EC50 values of 0.77 nM and 1.2 nM, respectively. Identifiers IUPAC name CAS Number…