Summary
5-Methoxy-2, N, N-dimethyltryptamine, often referred to as 5-MeO-2, N, N-TMT or 5-MeO-TMT, belongs to the tryptamine chemical class and possesses psychoactive properties as a psychedelic substance. It was initially synthesized by Alexander Shulgin and documented in his book “TiHKAL” (short for “Tryptamines I Have Known And Loved”).
When taken orally, 5-MeO-TMT is reported to produce psychoactive effects at a dosage ranging from 75 to 150 mg. However, these effects are relatively mild in comparison to other similar compounds. This suggests that the presence of a methyl group on the 2-position of the molecule may inhibit the binding of metabolic enzymes like monoamine oxidase (MAO). Simultaneously, it appears to interfere with the binding to and activation of the serotonin 5-HT2A receptor, which is the primary target responsible for mediating the hallucinogenic effects associated with such compounds.
| Identifiers | |
|---|---|
| IUPAC name | |
| CAS Number | 67292-68-6 |
|---|---|
| PubChem CID | 49756 |
| ChemSpider | 45143 |
| UNII | XZ2CCP18I2 |
| ChEMBL | ChEMBL7143 |
| CompTox Dashboard (EPA) | DTXSID10217627 |
| Chemical and physical data | |
| Formula | C14H20N2O |
| Molar mass | 232.327 g·mol−1 |
FAQ
1. What is 5-MeO-2,N,N-TMT?
5-MeO-2, N, N-TMT, also known as 5-MeO-TMT, is a psychoactive substance belonging to the tryptamine chemical class. It acts as a psychedelic drug and has been documented in Alexander Shulgin’s book “TiHKAL.”
2. Who first synthesized 5-MeO-2, N, N-TMT, and where is it reported?
5-MeO-2, N, N-TMT was first synthesized by Alexander Shulgin and reported in his book “TiHKAL,” which stands for “Tryptamines I Have Known And Loved.”
3. What are the psychoactive effects of 5-MeO-2, N, N-TMT, and at what dosage?
The psychoactive effects of 5-MeO-2, N, and N-TMT are reported to be relatively mild. It is claimed to produce such effects when taken orally at a dosage ranging from 75 to 150 mg.
4. How does 5-MeO-2, N, N-TMT’s chemical structure impact its effects?
The presence of a methyl group on the 2-position of the molecule in 5-MeO-2, N, N-TMT is thought to affect its interactions with metabolic enzymes like monoamine oxidase (MAO). Additionally, it may interfere with binding to and activation of the serotonin 5-HT2A receptor, the primary target responsible for producing the hallucinogenic effects commonly associated with such compounds.
5. Is 5-MeO-2, N, N-TMT legal and safe for recreational use?
The legal status of 5-MeO-2, N, N-TMT varies by country and region. Safety concerns also exist, as with any psychoactive substance. It is crucial to be aware of and abide by local laws and regulations, as well as to prioritize safety and responsible use.
6. Can 5-MeO-2, N, N-TMT be used for therapeutic purposes?
The therapeutic potential of 5-MeO-2, N, N-TMT has not been extensively studied. It is important to emphasize that the use of such substances for therapeutic purposes should only occur under the guidance of qualified medical professionals and in clinical settings.
7. Where can I find more information about 5-MeO-2, N, N-TMT?
For further information on 5-MeO-2, N, N-TMT, consider consulting scientific literature, academic research or speaking with healthcare professionals or experts in the field of psychoactive substances. Always prioritize safety and responsible use when considering the consumption of any such compounds.