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Summary
AM-2232, known chemically as 1-4-cyclobutyl)-3-(naphthalene-1-oyl)indole, is a potent yet non-specific agonist for cannabinoid receptors. It exhibits a Ki of 0.28 nM at CB1 and 1.48 nM at CB2, indicating its affinity for these receptor types.
In the United States, all CB1 receptor agonists belonging to the 3-(1-naphthyl)indole class, including AM-2232, are classified as Schedule I Controlled Substances.
| Identifiers | |
|---|---|
| IUPAC name | |
| CAS Number | 335161-19-8 |
|---|---|
| ChemSpider | 26633898 |
| UNII | 40KCH8YIKP |
| CompTox Dashboard (EPA) | DTXSID90187157 |
| Chemical and physical data | |
| Formula | C24H20N2O |
| Molar mass | 352.437 g·mol−1 |
FAQ
- What is AM-2232?
- AM-2232 is a synthetic compound with the chemical name 1-(4-cyclobutyl)-3-(naphthalene-1-oyl)indole. It is known for its interaction with cannabinoid receptors in the human body.
- How does AM-2232 work?
- AM-2232 functions as a cannabinoid receptor agonist. It binds to specific receptors, including CB1 and CB2, affecting various physiological processes.
- What are the effects of AM-2232?
- AM-2232 is reported to induce effects similar to those of cannabis, including altered perception, mood, and relaxation. These effects can vary depending on the individual and the dose.
- Is AM-2232 legal?
- In the United States, AM-2232 and similar compounds are classified as Schedule I Controlled Substances, meaning they are illegal to manufacture, possess, or distribute.
- Is AM-2232 safe for use?
- The safety of AM-2232 is a subject of concern. It is not approved for medical or recreational use, and its unregulated nature can lead to unpredictable risks and adverse effects.
- What is the recommended dosage for AM-2232?
- There is no established safe or recommended dosage for AM-2232. Its use is associated with a high potential for abuse and adverse health consequences.
- Are there legal alternatives to AM-2232?
- In many regions, there are legal and regulated alternatives available for those seeking the potential therapeutic benefits of cannabinoids. It is advisable to consult with a healthcare professional regarding these alternatives.
- Can AM-2232 be detected in drug tests?
- Yes, AM-2232 and similar compounds can often be detected in standard drug tests, as they can trigger positive results for cannabinoids.
- What are the potential health risks associated with AM-2232?
- The use of synthetic cannabinoids like AM-2232 has been linked to various health risks, including cardiovascular issues, psychiatric symptoms, and addiction. Long-term effects may not be well understood.
- Is AM-2232 available for research purposes?
- Researchers may obtain AM-2232 for legitimate scientific studies, but strict regulations and ethical guidelines must be followed when handling such substances.
References
- United States Patent 7241799 was granted on July 10, 2007, to Makriyannis A and Deng H for their work on “Cannabimimetic indole derivatives.”
- 21 U.S.C. § 812 delineates the Schedules of controlled substances in the United States, providing a framework for the classification and regulation of various substances.