Summary NM-2201, alternatively recognized as CBL-2201, belongs to the family of indole-based synthetic cannabinoids. It is theorized to exhibit analogous characteristics to its closely related counterparts, 5F-PB-22 and NNE1. These compounds are categorized as full agonists, demonstrating an indiscriminate binding…
Summary NE-CHMIMO (also known as CHM-018) is a synthetic cannabinoid with an indole base believed to act as a potent agonist of the CB1 receptor. It has gained prominence as a designer drug available for purchase online. NE-CHMIMO distinguishes itself…
Summary MAM-2201, also known as 4′-methyl-AM-2201 or 5″-fluoro-JWH-122 is believed to act as a potent agonist for cannabinoid receptors. This compound remained undocumented in scientific or patent literature until laboratories in the Netherlands and Germany first discovered it in June…
Summary JWH-424 is a member of the naphthoylindole family, characterized by its role as a cannabinoid agonist targeting both the CB1 and CB2 receptors. However, it demonstrates moderate selectivity for the CB2 receptor, with a Ki value of 5.44nM at…
Summary JWH-398 is an analgesic compound belonging to the naphthoylindole family, functioning as a cannabinoid agonist with activity at both the CB1 and CB2 receptors. It exhibits mild selectivity for CB1, demonstrating a Ki of 2.3 nM while registering 2.8…
Summary JWH-200, also known as WIN 55,225, is a member of the aminoalkylindole family, functioning as an analgesic compound with cannabinoid receptor agonist properties. This chemical exhibits a binding affinity, denoted as Ki, of 42 nM at the CB1 receptor,…
Summary JWH-198 is a medication hailing from both the aminoalkyl indole and naphthoylindole drug families, and it functions as a cannabinoid receptor agonist. This compound was initially developed by the pharmaceutical company Sanofi-Winthrop during the early 1990s. JWH-198 exhibits a…
Summary JWH-210, a member of the naphthoylindole family, is a potent analgesic compound. It is a robust cannabinoid agonist, acting on CB1 and CB2 receptors. It demonstrates a remarkable binding affinity with Ki values of 0.46 nM at CB1 and…
Summary JWH-149, a synthetic cannabimimetic compound, was initially identified by John W. Huffman. This substance is the N-pentyl analog of JWH-148. Notably, it demonstrates significant binding affinity for the CB2 receptor, with a Ki (inhibition constant) of approximately 0.73 ±…
Summary JWH-122, a synthetic cannabimimetic compound, was first identified by John W. Huffman. This compound is a methylated derivative of JWH-018 and exhibits a Ki of 0.69 nM at CB1 and 1.2 nM at CB2 receptors.In January 2015, a concerning…
