Summary JWH-116, a member of the naphthoylindole family, is a synthetic ligand that interacts with cannabinoid receptors. It represents the indole 2-ethyl variant of its closely related compound, JWH-018. JWH-116 exhibits a binding affinity for the CB1 receptor with a…
Summary JWH-098 belongs to the naphthoylindole family and is classified as a synthetic cannabinoid receptor agonist. It represents the indole 2-methyl variant of a closely related compound, JWH-081. Notably, JWH-098 exhibits distinctive binding preferences for the CB1 and CB2 receptors…
Summary JWH-081, a member of the naphthoylindole family, is an analgesic compound that functions as a cannabinoid agonist, affecting both CB1 and CB2 receptors. It exhibits a degree of selectivity for the CB1 subtype, with a Ki of 1.2nM, making…
Summary WH-073, a synthetic cannabinoid, is a member of the naphthoylindole family known for its analgesic properties. It functions as a partial agonist at both the CB1 and CB2 cannabinoid receptors, displaying a degree of selectivity for the CB1 subtype,…
Summary JWH-019, a member of the naphthoylindole family, is recognized as an analgesic compound acting as a cannabinoid agonist at both CB1 and CB2 receptors. Notably, it is the N-hexyl homolog of the known synthetic cannabinoid JWH-018. In contrast to…
Summary JWH-015, a member of the naphthoylindole family, functions as a cannabinoid agonist with subtype selectivity. Notably, it exhibits a high affinity for CB2 receptors, with a binding relationship of 13.8 nM, while its affinity for CB1 receptors is notably…
Summary JWH-007, a member of the naphthoylindole family, is a chemical compound primarily recognized for its analgesic properties. It functions as a cannabinoid agonist, engaging both CB1 and CB2 receptors. This compound was initially documented in 1994, and its discovery…
Summary FUB-JWH-018, sometimes referred to as FUB-018, is a synthetic cannabinoid derived from naphthoylindole. It can be described as a molecular hybrid, combining elements of JWH-018 and AB-FUBICA or ADB-FUBICA. Identifiers IUPAC name CAS Number 2365471-45-8 ChemSpider 34450892 UNII U0Z5KO073G…
Summary EAM-2201, also known as 4′-ethyl-AM-2201, 5″-fluoro-JWH-210, or SGT-14, is a substance believed to function as a potent agonist for cannabinoid receptors. This compound was not documented in scientific or patent literature until Japanese laboratories initially detected it in July…
Summary AM-2232, known chemically as 1-4-cyclobutyl)-3-(naphthalene-1-oyl)indole, is a potent yet non-specific agonist for cannabinoid receptors. It exhibits a Ki of 0.28 nM at CB1 and 1.48 nM at CB2, indicating its affinity for these receptor types.In the United States, all…
