Summary JWH-398 is an analgesic compound belonging to the naphthoylindole family, functioning as a cannabinoid agonist with activity at both the CB1 and CB2 receptors. It exhibits mild selectivity for CB1, demonstrating a Ki of 2.3 nM while registering 2.8…
Summary JWH-200, also known as WIN 55,225, is a member of the aminoalkylindole family, functioning as an analgesic compound with cannabinoid receptor agonist properties. This chemical exhibits a binding affinity, denoted as Ki, of 42 nM at the CB1 receptor,…
Summary JWH-198 is a medication hailing from both the aminoalkyl indole and naphthoylindole drug families, and it functions as a cannabinoid receptor agonist. This compound was initially developed by the pharmaceutical company Sanofi-Winthrop during the early 1990s. JWH-198 exhibits a…
Summary JWH-210, a member of the naphthoylindole family, is a potent analgesic compound. It is a robust cannabinoid agonist, acting on CB1 and CB2 receptors. It demonstrates a remarkable binding affinity with Ki values of 0.46 nM at CB1 and…
Summary JWH-149, a synthetic cannabimimetic compound, was initially identified by John W. Huffman. This substance is the N-pentyl analog of JWH-148. Notably, it demonstrates significant binding affinity for the CB2 receptor, with a Ki (inhibition constant) of approximately 0.73 ±…
Summary JWH-122, a synthetic cannabimimetic compound, was first identified by John W. Huffman. This compound is a methylated derivative of JWH-018 and exhibits a Ki of 0.69 nM at CB1 and 1.2 nM at CB2 receptors.In January 2015, a concerning…
Summary JWH-116, a member of the naphthoylindole family, is a synthetic ligand that interacts with cannabinoid receptors. It represents the indole 2-ethyl variant of its closely related compound, JWH-018. JWH-116 exhibits a binding affinity for the CB1 receptor with a…
Summary JWH-098 belongs to the naphthoylindole family and is classified as a synthetic cannabinoid receptor agonist. It represents the indole 2-methyl variant of a closely related compound, JWH-081. Notably, JWH-098 exhibits distinctive binding preferences for the CB1 and CB2 receptors…
Summary JWH-081, a member of the naphthoylindole family, is an analgesic compound that functions as a cannabinoid agonist, affecting both CB1 and CB2 receptors. It exhibits a degree of selectivity for the CB1 subtype, with a Ki of 1.2nM, making…
Summary WH-073, a synthetic cannabinoid, is a member of the naphthoylindole family known for its analgesic properties. It functions as a partial agonist at both the CB1 and CB2 cannabinoid receptors, displaying a degree of selectivity for the CB1 subtype,…
