Category Naphthoylindoles

AM-1235

Summary AM-1235, also known as 1-(5-fluorophenyl)-3-(naphthalene-1-oyl)-6-nitroindole, is a potent and moderately selective agonist targeting the cannabinoid receptor CB1. Identifiers IUPAC name CAS Number 335161-27-8  ChemSpider 26633899  UNII 2HV9AH611M CompTox Dashboard (EPA) DTXSID10187159 Chemical and physical data Formula C24H21FN2O3 Molar mass…

AM-1221

Summary AM-1221 is a potent and selective agonist that primarily targets the cannabinoid receptor CB2, exhibiting a remarkable Ki of 0.28 nM at CB2 and 52.3 Nm at CB1. This translates to an approximately 180-fold preference for CB2 over CB1.…

AM-1220

Summary AM-1220 is recognized for its potent and moderately selective agonistic effects on the cannabinoid receptor CB1, demonstrating approximately 19-fold selectivity for CB1 compared to the related CB2 receptor. This compound initially emerged in the early 1990s as a creation…