Summary AM-1235, also known as 1-(5-fluorophenyl)-3-(naphthalene-1-oyl)-6-nitroindole, is a potent and moderately selective agonist targeting the cannabinoid receptor CB1. Identifiers IUPAC name CAS Number 335161-27-8 ChemSpider 26633899 UNII 2HV9AH611M CompTox Dashboard (EPA) DTXSID10187159 Chemical and physical data Formula C24H21FN2O3 Molar mass 404.441 g·mol−1 Pharmacology Pharmacodynamics AM-1235 functions as a cannabinoid receptor agonist, with a Ki value of …
Summary AM-1221 is a potent and selective agonist that primarily targets the cannabinoid receptor CB2, exhibiting a remarkable Ki of 0.28 nM at CB2 and 52.3 Nm at CB1. This translates to an approximately 180-fold preference for CB2 over CB1. The presence of both 2-methyl and 6-nitro groups on the indole ring contributes to enhanced …
Summary AM-1220 is recognized for its potent and moderately selective agonistic effects on the cannabinoid receptor CB1, demonstrating approximately 19-fold selectivity for CB1 compared to the related CB2 receptor. This compound initially emerged in the early 1990s as a creation by a team led by Thomas D’Ambra at Sterling Winthrop. In the subsequent years, AM-1220 …
JWH-018, a synthetic cannabinoid, has gained notoriety as a popular research chemical. With its proliferation, many online sellers have emerged, offering this designer drug for sale. However, the landscape of JWH-018 research chemical vendors warrants a critical review, given the potential risks of purchasing and using such substances.First and foremost, the online sale of JWH-018 …
AM-2201, a synthetic cannabinoid, has gained notoriety in recent years for its potential for misuse and adverse health effects. As such, the sale of this research chemical is tightly regulated in many countries. Consequently, those seeking to buy AM-2201 often turn to online vendors, where many options are available. However, navigating the murky waters of …
