Alan Weed

Etonitazen

by

Summary Etonitazene, also referred to as EA-4941 or CS-4640, is a benzimidazole opioid. Its discovery dates back to 1957. Studies have indicated that it possesses an astonishing potency level, estimated to be roughly 1,000 to 1,500 times more potent than morphine when tested in animals.Due to its marked potential for causing dependence and a propensity … Read more

U-47700

by

Summary U-47700 also recognized as U4, pink heroin, pinky, or pink, is an opioid analgesic drug initially developed by a team at Upjohn during the 1970s. In animal models, it boasts approximately 7.5 times the potency of morphine.A physical sample of U-47700 is available for reference.This compound is a structural isomer of the earlier opioid … Read more

Mazindol

by

Summary Mazindol, available under brand names such as Mazanor and Sanorex, is classified as a stimulant medication primarily employed for appetite suppression. This medication was originally formulated by Sandoz-Wander during the 1960s. Identifiers IUPAC name CAS Number 22232-71-9  PubChem CID 4020 IUPHAR/BPS 4797 DrugBank DB00579  ChemSpider 3880  UNII C56709M5NH KEGG D00367  ChEMBL ChEMBL781  CompTox Dashboard … Read more

Diclofensine

by

Summary Diclofensine (Ro 8-4650) emerged from Hoffmann-La Roche’s research efforts in the 1970s aimed at discovering a novel antidepressant. Subsequent investigations revealed that the active component was the (S)-isomer. This compound functions as a stimulant by operating as a triple monoamine reuptake inhibitor, primarily impeding the reuptake of dopamine and norepinephrine, exhibiting binding affinities (Ki) … Read more

Bromantane

by

Summary Bromantane, marketed under the brand name Ladasten, is an unconventional psychostimulant and anxiolytic medication belonging to the adamantane family, sharing connections with amantadine and memantine. It finds usage in Russia for the treatment of neurasthenia. Although researchers have established that bromantane’s effects are tied to the dopaminergic and potentially serotonergic neurotransmitter systems, the precise … Read more

Amfonelic

by

Summary Amfonelic acid (AFA), also known as WIN 25,978, is a research compound and dopaminergic stimulant that possesses antibiotic characteristics. While there is a scarcity of extensive clinical trials involving AFA, it is predominantly employed within the realm of scientific research. Identifiers IUPAC name CAS Number 15180-02-6  PubChem CID 2137 ChemSpider 2052  UNII RR302AR19Y KEGG … Read more

2-Aminoindane

by

Summary 2-Aminoindane (2-AI) is a compound utilized in scientific research for its potential in addressing neurological conditions and supporting psychotherapy practices. Additionally, it has found its way into the market as a designer drug. Its primary mechanism of action involves its selective interaction with the norepinephrine transporter (NET) and dopamine transporter (DAT). Identifiers IUPAC name … Read more

Viloxazine

by

Summary Viloxazine, available under the brand name Qelbree and formerly known as Vivalan and by other trade names, is a medication classified as a selective norepinephrine reuptake inhibitor (NRI). It is employed in the treatment of attention deficit hyperactivity disorder (ADHD) in both children and adults. Interestingly, Viloxazine had a prior history of almost three … Read more

4,4′-Dimethylaminorex

by

Summary 4,4′-Dimethylaminorex, commonly referred to as 4,4′-DMAR and colloquially known as “Serotonin,” belongs to the category of psychostimulant and entactogen designer drugs. This compound shares chemical similarities with aminorex, 4-methylaminorex, and pemoline. It was initially identified in the Netherlands in December 2012 and subsequently emerged in the European designer drug market around mid-2013.By February 2014, … Read more

2-Diphenylmethylpyrrolidine

by

Summary 2-Diphenylmethylpyrrolidine, also known as Desoxy-D2PM or 2-benzhydrylpyrrolidine, is a psychoactive stimulant drug. This compound is a structural analogue of diphenylprolinol (D2PM) with the removal of the hydroxyl group, and it shares structural similarities with desoxypipradrol (2-DPMP). Both D2PM and 2-DPMP function as norepinephrine-dopamine reuptake inhibitors (NDRIs). Desoxy-D2PM has been marketed and used as a … Read more