Summary W-18 belongs to a group of 32 compounds designated as W-1 to W-32, initially developed during research on analgesic drug discovery in the 1980s. While it was first synthesized at the University of Alberta as part of this analgesic…
Summary Tolibut, scientifically known as 3-(p-tolyl)-4-aminobutyric acid or β-(4-methylphenyl)-GABA, is a pharmaceutical compound developed in Russia. This substance is categorized as a derivative of γ-aminobutyric acid (GABA), making it a GABA analog. Specifically, halibut is the 4-methyl variant of phenibut…
Summary Phenibut, available under various brand names such as Anvifen, Fenibut, and Noofen, is a central nervous system depressant known for its anxiolytic properties. It is prescribed to address conditions like anxiety, insomnia, and other related indications. Typically administered orally…
Summaru Pagoclone, a member of the cyclopyrrolone family, is classified as an anxiolytic agent, sharing its lineage with more familiar drugs like the sleep aid zopiclone. This compound was initially synthesized by a team of French researchers working for Rhone-Poulenc…
Summary Benzylbutylbarbiturate, scientifically referred to as 5-benzyl-5-n-butylbarbituric acid, stands as an uncommon instance of a designer drug within the barbiturate class, potentially one of the few of its kind identified in recent times. This substance came to the attention of…
Summary 4-Fluorophenibut, which also goes by the developmental code name CGP-11130, is recognized as β-(4-fluorophenyl)-γ-aminobutyric acid or β-(4-fluorophenyl)-GABA. It operates as an agonist for the GABAB receptor, although it never reached the commercial market.In its selectivity, 4-Fluorophenibut demonstrates a preference…
Summary 2-Methyl-2-pentanol, also known by its IUPAC name, 2-methylpentan-2-ol, is an organic chemical compound. It finds utility in gas chromatography as an additive for the differentiation of branched compounds, particularly alcohols, due to its unique properties.Moreover, the detection of 2-Methyl-2-pentanol…
Summary Throughout its history, Trichloroethanol (TAA) has served as an anesthetic, as documented in the past. More recently, it has gained notoriety as a recreational drug. TAA primarily functions as a positive allosteric modulator for GABAA receptors, akin to ethanol.…
