Summary RCS-8, also known as 1-(2-cyclohexyl ethyl)-3-(2-methoxyphenylacetyl)indole and referred to as SR-18 and BTM-8, is a synthetic cannabinoid that has been identified as an ingredient in “herbal” synthetic cannabis mixtures. Structurally, it can be characterized as an analog of JWH-250,…
Summary JWH-251, scientifically referred to as 1-pentyl-3-(2-methylphenylacetyl)indole, belongs to the phenylacetylindole family, characterized as a synthetic cannabinoid. It acts as a cannabinoid agonist, exhibiting approximately five times more selectivity for CB1 receptors, with a Ki of 29 nM, compared to…
Summary JWH-250, scientifically known as 1-pentyl-3-(2-methoxyphenylacetyl)indole, is a member of the phenylacetylindole family recognized for its analgesic properties. This chemical compound operates as a cannabinoid agonist, engaging with CB1 and CB2 receptors, featuring a Ki of approximately 11 nM at…
Summary JWH-249, also known as 1-pentyl-3-(2-bromophenylacetyl)indole, is a synthetic cannabinoid belonging to the phenylacetylindole family. It operates as a cannabinoid agonist with approximately 2.4 times higher selectivity for CB1 receptors, having a Ki of roughly 8.4 ± 1.8 nM, compared…
Summary JWH-203, also known as 1-pentyl-3-(2-chlorophenylacetyl)indole, is a member of the phenylacetylindole family and serves as an analgesic chemical. This compound functions as a cannabinoid agonist, demonstrating nearly equal affinity for CB1 and CB2 receptors, with a Ki of approximately…
Summary JWH-167, also known as 1-pentyl-3-(phenylacetyl)indole, is a synthetic cannabinoid belonging to the phenylacetylindole family. This compound acts as a cannabinoid agonist with approximately 1.75 times higher selectivity for CB1 receptors, exhibiting a Ki of about 90 nM ± 17…
Summary NM-2201, alternatively recognized as CBL-2201, belongs to the family of indole-based synthetic cannabinoids. It is theorized to exhibit analogous characteristics to its closely related counterparts, 5F-PB-22 and NNE1. These compounds are categorized as full agonists, demonstrating an indiscriminate binding…
Summary NE-CHMIMO (also known as CHM-018) is a synthetic cannabinoid with an indole base believed to act as a potent agonist of the CB1 receptor. It has gained prominence as a designer drug available for purchase online. NE-CHMIMO distinguishes itself…
Summary MAM-2201, also known as 4′-methyl-AM-2201 or 5″-fluoro-JWH-122 is believed to act as a potent agonist for cannabinoid receptors. This compound remained undocumented in scientific or patent literature until laboratories in the Netherlands and Germany first discovered it in June…
Summary JWH-424 is a member of the naphthoylindole family, characterized by its role as a cannabinoid agonist targeting both the CB1 and CB2 receptors. However, it demonstrates moderate selectivity for the CB2 receptor, with a Ki value of 5.44nM at…
