Etaqualone

Summary Methaqualone, known by trade names such as Aolan, Athinazone, and Ethinazone, belongs to the quinazolinone class of compounds. This substance is a GABAergic agent and serves as an analog of methaqualone. It was initially developed during the 1960s and found its primary market in France and a few other European countries. Ethaqualone exhibits various … Read more

Afloqualone

Summary Afloqualone, also known as Arofuto, belongs to the quinazolinone family of GABAergic drugs. It is an analog of methaqualone that was developed in the 1970s by researchers at Tanabe Seiyaku. This compound exerts sedative and muscle-relaxant effects through its agonistic activity at the β subtype of the GABA receptor. Afloqualone has found some clinical … Read more

γ-Valerolactone

Summary γ-Valerolactone, often abbreviated as GVL, represents an organic compound characterized by the chemical formula C5H8O2. This clear, colourless liquid ranks among the more prevalent lactones. Although GVL possesses chirality, it is commonly employed in its racemic form. It can be readily derived from cellulosic biomass and holds promise as both a potential fuel source … Read more

gamma-Hydroxyvaleric acid

Summary Gamma-hydroxyvaleric acid (GHV), also referred to as 4-methyl-GHB, is a synthetic substance classified as a designer drug closely related to gamma-hydroxybutyric acid (GHB). Occasionally, it appears on the grey market as a legal substitute for GHB. However, it is characterized by lower potency and increased toxicity compared to GHB, factors that have, in practice, … Read more

gamma-Butyrolactone

Summary Gamma-butyrolactone (GBL), also known as γ-butyrolactone, is a colourless liquid that readily absorbs moisture from the air and has a faint, distinct odour. This compound represents the simplest form of a four-carbon lactone. Its primary application lies in serving as an intermediate compound for the synthesis of various other chemicals, including methyl-2-pyrrolidone.In the context … Read more

1,4-Butanediol

Summary Butane-1,4-diol, distinct from 1,3-butanediol, represents primary alcohol and an organic compound identified by the chemical formula HOCH2CH2CH2CH2OH. This substance is a clear and thick liquid, comprising one of the four enduring isomeric forms of butanediol. Identifiers CAS Number 110-63-4  3D model (JSmol) Interactive imageInteractive image ChEBI CHEBI:41189  ChEMBL ChEMBL171623  ChemSpider 13835209  DrugBank DB01955  ECHA … Read more

Metizolam

Summary Metizolam, alternatively recognized as desmethyl etizolam, stands as a thienotriazolodiazepine, characterized by its status as the demethylated counterpart of the closely linked etizolam. Identifiers IUPAC name CAS Number 40054-68-0  PubChem CID 12434325 ChemSpider 59207712 UNII K1C6XI9LLX ChEMBL ChEMBL4782672 Chemical and physical data Formula C16H13ClN4S Molar mass 328.82 g·mol−1 Legal status After being offered as a … Read more

Fluclotizolam

Summary Fluclotizolam, initially synthesised in 1979 as a thienotriazolodiazepine derivative, remained unmarketed at the time. However, it resurfaced as a designer drug and was definitively identified for this purpose in 2017. Identifiers IUPAC name CAS Number 54123-15-8 PubChem CID 21317700 ChemSpider 15332007 UNII 4Z9Y7GEG8Z Chemical and physical data Formula C15H10ClFN4S Molar mass 332.78 g·mol−1 FAQ References

Flubrotizolam

Summary Flubrotizolam, known chemically as 2-bromo-4-(2-fluorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine, is a thienotriazolodiazepine analog. It possesses significant sedative and anxiolytic properties, and it has been marketed and distributed as a substance falling under the category of designer drugs. Identifiers IUPAC name CAS Number 57801-95-3  PubChem CID 3044878 UNII ZWK85P59MH CompTox Dashboard (EPA) DTXSID80206503 Chemical and physical data Formula C15H10BrFN4S … Read more

Etizolam

Summary Etizolam, available under numerous brand names, is a derivative of thienodiazepine, essentially an analogue of benzodiazepine. It distinguishes itself by substituting the benzene ring with a thiophene ring and fusing a triazole ring, effectively categorizing it as a thienotriazolodiazepine.Although categorized as a thienodiazepine, Etizolam is clinically treated as a benzodiazepine due to its mechanism … Read more