Summary ADBICA, also known as ADB-PICA, surfaced as a designer drug within synthetic cannabis blends in Japan back in 2013. Notably, before its inclusion as a component of synthetic cannabis blends, ADBICA had remained absent from scientific literature. This compound shares a distinctive feature with SDB-001 and STS-135, namely the presence of a carboxamide group …
Summary ADB-FUBICA is a pharmaceutical compound that exerts substantial agonistic effects on cannabinoid receptors, displaying EC50 values of 2.6 nM at CB1 and 3.0 nM at CB2. Identifiers IUPAC name CAS Number 1801338-23-7 UNII S3ABP24K72 Chemical and physical data Formula C22H24FN3O2 Molar mass 381.451 g·mol−1 FAQ 1. What is ADB-FUBICA? ADB-FUBICA is a chemical compound that …
Summary ADB-FUBIATA, also known as AD-18 or FUB-ACADB, emerged as a synthetic cannabinoid compound in 2021. It shares structural similarities with the older combination ADB-FUBICA, with a notable distinction – an extended amide linker group by adding a methylene bridge. This compound found its way into the market as an ingredient in grey-market synthetic cannabis …
Summary AB-PICA exhibits significant potency as an agonist for both the CB1 receptor (with an EC50 of 12 nM) and the CB2 receptor (also with an EC50 of 12 nM). Identifiers IUPAC name CAS Number 1801338-24-8 1445583-48-1 (racemate) UNII BWQ0BJ2OGXQ71G788A6H Chemical and physical data Formula C19H27N3O2 Molar mass 329.444 g·mol−1 fAQ 1. What is AB-PICA? AB-PICA is …
Summary AB-FUBICA is a compound that is a potent agonist for cannabinoid receptors, displaying notable EC50 values of 21 nM at CB1 and 15 nM at CB2. Identifiers IUPAC name CAS Number 1801338-22-6 ChemSpider 57427397 UNII U6SUE53VVY Chemical and physical data Formula C21H22FN3O2 Molar mass 367.424 g·mol−1 FAQ References
Summary AB-005, also known as 1-[(1-methylpiperidin-2-yl)methyl]-1H-indol-3-yl-methanone, is a designer drug offered by online vendors, positioned as a cannabimimetic agent. This compound’s structure and pharmacological activity were first documented in 2010, well before its availability in the commercial market in 2012. Studies revealed that AB-005 exhibits a notable affinity for CB1 receptors (Ki = 5.5 nM) and …
Summary 5F-SDB-006 is a substance known to function as a potent agonist for cannabinoid receptors. It exhibits an EC50 of 50 nM for human CB1 receptors and 123 nM for human CB2 receptors. This compound was first identified during investigations into the closely related substance APICA, which had been illicitly marketed under the name “2NE1”. …
Summary 5F-NNE1, also recognized by its aliases 5F-NNEI and 5F-MN-24, represents an indole-derived synthetic cannabinoid. This compound is believed to act as a robust agonist of the CB1 receptor and has been made available for purchase on online platforms as a designer drug. It’s noteworthy that, in connection with the related substance APINACA, which has …
Summary MMB-2201, known by various aliases such as 5F-MMB-PICA, 5F-AMB-PICA, and I-AMB, is a potent synthetic cannabinoid founded on the indole-3-carboxamide structure. This compound has gained notoriety for its presence in the designer drug market and its use as an active component in synthetic cannabis blends. While it initially emerged in Russia and Belarus in …
Summary 5F-ADBICA, also referred to as 5F-ADB-PICA, is an indole-derived synthetic cannabinoid recognized for its agonistic solid activity at both CB1 and CB2 receptors, displaying remarkable EC50 values of 0.77 nM and 1.2 nM, respectively. Identifiers IUPAC name CAS Number 1801338-27-1 PubChem CID 118796421 ChemSpider 52085200 UNII U9H280G9O7 Chemical and physical data Formula C20H28FN3O2 Molar …
