Summary 4-Fluoromethamphetamine (4-FMA) is a stimulant substance that shares a chemical relationship with methamphetamine and 4-fluoroamphetamine. While it has been observed as being available as a designer drug, comprehensive knowledge regarding its pharmacological properties and potential toxicity remains limited.Initially emerging in the context of legal highs in Japan around 2006, it later faced legal restrictions …
Summary 4-Fluoroamphetamine (4-FA), also recognized as 4-FMP, PAL-303, or “Flux,” and alternatively referred to as para-fluoroamphetamine (PFA), belongs to the realm of psychoactive research chemicals, falling within the phenethylamine and substituted amphetamine categories. It is characterized by its capacity to induce both stimulating and entactogenic effects. In recreational contexts, 4-FA is occasionally available alongside analogous …
Summary Para-chloroamphetamine (PCA), also recognized as 4-chloroamphetamine (4-CA), falls within the category of substituted amphetamines and serves as a monoamine releaser. It shares similarities with MDMA but is notably more neurotoxic, primarily attributed to the uncontrolled release of both serotonin and dopamine by a metabolite.This compound is frequently employed by neurobiologists as a neurotoxin for …
Summary Parabromoamphetamine (PBA), alternatively referred to as 4-bromoamphetamine (4-BA), belongs to the amphetamine family and functions as a serotonin-norepinephrine-dopamine releasing agent (SNDRA), resulting in stimulant properties.In addition, there is a closely related compound known as parabromomethamphetamine, identified under the codename V-111. Identifiers IUPAC name CAS Number 18455-37-3 PubChem CID 205668 ChemSpider 178189 UNII 6IBU62D1N2 ChEMBL …
Summary 5-(2-Aminopropyl)indole, also known as 5-API, 5-IT, or PAL-571, is a compound belonging to the indole and phenethylamine families, and it is known for its empathogenic effects. This substance was initially synthesized by Albert Hofmann in 1962. Since 2011, it has been openly marketed as a designer drug and sold by online vendors for recreational …
Summary NM-2-AI, also known as N-methyl-2-aminoindane, is a psychoactive substance and a research chemical that has been distributed via online platforms as a designer drug. Structurally, it is a rigid counterpart to methamphetamine and is derived from 2-aminoindane. Identifiers IUPAC name CAS Number 24445-44-1HCl: 10408-85-2 PubChem CID 15023225 ChemSpider 13566342 UNII ZLW84Y27HG ChEMBL ChEMBL1188235 CompTox Dashboard …
Summary MEAI, also known as 5-methoxy-2-aminoindane, 5-MeO-AI, or Chaperon, belongs to the family of indane molecules. Its molecular structure made its initial, albeit implicit, appearance within a patent document back in 1998. Subsequently, it was explicitly and pharmacologically described in a peer-reviewed paper in 2017 by David Nutt and Ezekiel Golan, among others. Further insights …
Summary 5-(2-Aminopropyl)-2,3-dihydro-1H-indene (commonly known as 5-APDI or indanylaminopropane/IAP) is a member of the amphetamine family, with diverse aliases including IAP (psychedelic), 2-API (2-aminopropylindane), indanametamine, and, occasionally, indanylamphetamine. This compound is recognized for its entactogenic and psychedelic properties. 5-APDI and Its Availability: 5-APDI has been accessible through online vendors on the internet and has been present …
Summary 5,6-Methylenedioxy-N-methyl-2-aminoindane, commonly referred to as MDMAI is a compound created in the 1990s by a research team led by David E. Nichols at Purdue University. In animal studies, it operates as a selective serotonin-releasing agent (SSRA) without neurotoxic effects, while in humans, it is believed to have the potential to act as an entactogen, …
Summary Putylone, alternatively referred to as β-keto-1,3-benzodioxolyl-N-propyldioxybutanamine, bk-PBDB, and N-propylbutylone, emerged on the scene in 2023. This stimulant and empathogenic compound came into the spotlight, notably around the time when a ban was imposed on its related combination, eutylone. Identifiers IUPAC name CAS Number 802855-66-9 HCl: 802286-81-3 PubChem CID 122129922 ChemSpider 480488897 UNII 46BQ874756HCl: 46BQ874756 Chemical and physical …
