Summary N-Ethylnorketamine, also known as eth ketamine, NENK, or 2-Cl-2′-Oxo-PCE, is a designer drug believed to share characteristics with ketamine. Ketamine is a dissociative anesthetic drug recognized for its hallucinogenic and sedative effects. N-Ethylnorketamine emerged in online markets around September 2012 and has been detected in drug samples seized by analytical laboratories in the UK …
Summary Methoxyketamine, also known as 2-MeO-2-deschloroketamine, is a designer drug belonging to the arylcyclohexylamine class. It was initially documented in 1963. This compound serves as an analog to ketamine, with the chlorine atom replaced by a methoxy group. Its synthesis, involving the rearrangement of an amino ketone, has been detailed in reports.Being classified as an …
Summary MXiPr, also known as Methoxisopropamine, Isopropyloxetamine, and Isopropyxetamine, is a recreational designer drug celebrated for its dissociative effects. It falls under the arylcyclohexylamine derivative category, sharing kinship with well-known substances like ketamine and methoxetamine. This compound was initially detected in Slovenia in December 2020 and became subject to legal restrictions, being prohibited in Hungary …
Summary Methoxpropamine, also known as MXPr and 2-Oxo-3′-methoxy-PCPr, falls within the category of dissociative anesthetic drugs belonging to the arylcyclohexylamine class. It functions as an NMDA receptor antagonist. Methoxpropamine shares structural similarities with other substances like methoxetamine and PCPr. This compound has been marketed online as a designer drug and was initially detected in Denmark …
Summary Methoxetamine, which is also recognized under names such as 3-MeO-2′-Oxo-PCM, MXM, and MMXE, belongs to the arylcyclohexylamine class of dissociative anesthetics. It shares close structural similarities with substances like methoxetamine and methoxetamine. Methoxetamine has gained popularity as a designer drug available for purchase on the internet. Identifiers IUPAC name CAS Number 1781829-56-8 PubChem CID …
Summary Methoxetamine, often abbreviated as MXE, is a dissociative hallucinogenic substance that has been distributed as a designer drug. What sets it apart from many dissociatives, such as ketamine and phencyclidine (PCP), developed initially as pharmaceutical anesthetics, is that MXE was intentionally crafted to enhance the antidepressant effects of ketamine.MXE belongs to the class of …
Summary Eticyclidine (PCE, CI-400) is a dissociative anesthetic substance renowned for its hallucinogenic properties. It shares similarities in effects with phencyclidine but is marginally more potent. Developed by Parke-Davis during the 1970s, PCE underwent anesthetic evaluation under the codename CI-400. However, research into PCE was discontinued following the emergence of ketamine, a comparable drug with …
Summary Deschloroketamine (DXE, DCK, 2′-Oxo-PCM) is a dissociative anesthetic compound available through online sources as a designer drug. Additionally, it has been suggested for potential use in the treatment of bacterial, fungal, viral, or protozoal infections, as well as for immunomodulation at a dosage of 2 mg per day. Identifiers IUPAC name CAS Number 7063-30-1 hydrochloride: 4631-27-0 …
Summary 4-Methoxyphencyclidine, also known as methoxydine or 4-MeO-PCP, is a dissociative anesthetic drug that has been made available for purchase as a research chemical via online channels. The synthesis of 4-MeO-PCP traces back to 1965 when Victor Maddox, a medicinal chemist at Parke-Davis, first documented its production. In 1999, an anonymous chemist using the pseudonym …
Summary 3-Methoxyphencyclidine (3-MeO-PCP) belongs to the arylcyclohexylamine class and is a dissociative hallucinogenic substance closely related to phencyclidine (PCP). It has been available for purchase online as a designer drug. This compound primarily functions as an antagonist of the NMDA receptor. Additionally, it has been observed to interact with the sigma σ1 receptor and the …
