4-HO-EPT, also known as 4-hydroxy-N-ethyl-N-propyltryptamine, is an infrequently encountered chemical compound in the tryptamine class. It shares a structural similarity with psilocin (4-HO-DMT).

CAS Number2595431-59-5 [PubChem]
3D model (JSmol)Interactive image
Chemical formulaC15H22N2O
Molar mass246.354 g·mol−1


United Kingdom: The use of 4-HO-EPT is prohibited in the United Kingdom due to the enactment of the Psychoactive Substances Act of 2016.

United States: In the United States, 4-HO-EPT may fall under the psilocin analogs, regulated as Schedule I substances under the Controlled Substances Act. Consequently, selling 4-HO-EPT for human consumption would be unlawful under the Federal Analogue Act.


1. What is 4-HO-EPT?

  • 4-HO-EPT, or 4-hydroxy-N-ethyl-N-propyltryptamine, is a chemical compound in the tryptamine class structurally related to psilocin (4-HO-DMT).

2. Is 4-HO-EPT legal in the United Kingdom?

  • No, 4-HO-EPT is illegal in the United Kingdom due to its inclusion in the Psychoactive Substances Act of 2016.

3. What is the legal status of 4-HO-EPT in the United States?

  • In the United States, 4-HO-EPT may be considered an analog of psilocin, a Schedule I drug under the Controlled Substances Act. Its sale for human consumption is illegal under the Federal Analogue Act.

4. Are there any known effects associated with 4-HO-EPT use?

  • Information on the effects of 4-HO-EPT is limited, given its rarity. Users have reported experiences resembling those associated with other psychedelics, such as altered perception, changes in mood, and hallucinations. However, individual reactions can vary.

5. Are there any safety precautions for using 4-HO-EPT?

  • As with any psychedelic substance, caution is crucial. Start with a low dose in a safe and controlled environment. Consider having a sober and experienced sitter present. Be aware of potential interactions with other substances and any personal medical conditions.

6. How can one ensure the purity of 4-HO-EPT?

  • To ensure the substance’s purity, obtaining it from reputable sources is advisable. Additionally, you can have samples tested by analytical methods if you doubt their authenticity.

7. Is 4-HO-EPT used for medical or therapeutic purposes?

  • Currently, 4-HO-EPT is not recognized for medical or therapeutic applications. Its use is primarily experimental, and more research is needed to understand its potential benefits or risks.

8. How does 4-HO-EPT compare to other psychedelics like psilocybin or LSD?

  • 4-HO-EPT shares structural similarities with psilocin but may have distinct effects and experiences associated with its use. Each psychedelic substance is unique in its action and potential effects.

9. Where can I find more information about 4-HO-EPT?

  • You can find more information about 4-HO-EPT in scientific literature, research papers, and online resources dedicated to psychedelics. Ensure that the information you access is from reputable sources.


  1. “Misuse of Drugs Act 1971 (Legislation.gov.uk)”.

Leave a Comment

Your email address will not be published. Required fields are marked *