4-Methoxybutyrfentanyl, commonly referred to as 4-MeO-BF, is categorized as an opioid analgesic. It shares structural similarities with buy fentanyl and has gained notoriety as a designer drug available for purchase on online platforms.

IUPAC name
CAS Number2088842-68-4
PubChem CID118796493
Chemical and physical data
Molar mass380.532 g·mol−1

Adverse Effects

The side effects associated with fentanyl analogs mirror those of fentanyl itself, encompassing symptoms like itching, nausea, and the potential for severe respiratory depression. This condition can pose a life-threatening risk. Throughout Europe and the former Soviet republics, the resurgence of fentanyl analog use since the early 2000s, starting in Estonia, has tragically claimed the lives of hundreds. Moreover, novel derivatives of these substances continue to emerge, maintaining a grave concern for public safety.

Legal status

4-Methoxybutyrfentanyl was classified as illegal in Sweden as of January 26, 2016.
In the United States, 4-Methoxybutyrfentanyl is categorized as a Schedule I controlled substance, a designation that has been in effect since February 1, 2018.


1. What is 4-Methoxybutyrfentanyl (4-MeO-BF)?

4-Methoxybutyrfentanyl, commonly known as 4-MeO-BF, is a synthetic opioid analgesic. It is chemically related to fentanyl and is often classified as a fentanyl analog.

2. How is 4-methoxybutyrfentanyl used?

4-MeO-BF is typically used in powder or crystalline form. It is known to be consumed through various routes, including oral ingestion, nasal inhalation, or intravenous injection. However, its use is dangerous and illegal in many places.

3. What are the effects of 4-methoxybutyrfentanyl?

The effects of 4-MeO-BF are similar to those of fentanyl, including pain relief and euphoria. However, it also carries serious risks, such as potential respiratory depression, which can be life-threatening. Users may experience side effects like itching and nausea.

4. Is 4-Methoxybutyrfentanyl legal?

The legality of 4-MeO-BF varies by country and region. In some places, it is classified as a controlled substance and is illegal to manufacture, distribute, or possess. It is essential to check local laws and regulations regarding this substance.

5. Is 4-methoxybutyrfentanyl safe to use?

No, 4-MeO-BF is not safe for recreational or medicinal use. It is a potent opioid and carries a high risk of overdose and severe adverse effects, including death. Using this substance is strongly discouraged.

6. Can 4-methoxybutyrfentanyl be addictive?

Yes, like other opioids, 4-MeO-BF has the potential for addiction and physical dependence. Using it can lead to the development of tolerance and withdrawal symptoms when attempting to quit.

7. What are the potential dangers of 4-methoxybutyrfentanyl?

The dangers associated with 4-MeO-BF use include the risk of overdose, respiratory depression, and death. Additionally, it may contain impurities or be mixed with other harmful substances, further increasing the dangers of its consumption.

8. Are there any medical uses for 4-Methoxybutyrfentanyl?

No, 4-MeO-BF is not approved for any medical or therapeutic purposes. It is strictly intended for scientific research and should not be used outside of a controlled laboratory setting.

9. Where can I get help if I or someone I know is struggling with 4-methoxybutyrfentanyl addiction?

If you or someone you know is dealing with substance abuse or addiction related to 4-MeO-BF or any other opioid, it is crucial to seek professional help. Contact local addiction treatment centers, medical professionals, or addiction hotlines for guidance and support.

10. What steps can be taken to prevent 4-methoxybutyrfentanyl-related harm?

Preventing harm associated with 4-MeO-BF involves education, awareness, and strict adherence to legal regulations. Avoid using this substance, and encourage others to do the same. Promote responsible drug use and seek assistance for addiction or substance abuse issues promptly.


  1. 4-MeO-Butyrfentanyl – Leading in Synthetic Opioid Research Cayman Chemical is at the forefront of researching 4-MeO-Butyrfentanyl and its analogs. We are committed to advancing knowledge in the field of synthetic opioids.
  2. The Database on 4-Methoxybutyrfentanyl The “4-Methoxybutyrfentanyl” entry in the New Synthetic Drugs Database, archived since March 4, 2016, offers valuable insights into this synthetic opioid. Information retrieved on February 6, 2016, continues to contribute to our understanding of this compound.
  3. Analyzing 4-MeO-BF An analytical report on “4-MeO-BF” in PDF format was conducted as part of the European project RESPONSE. This report sheds light on the chemical properties and characteristics of 4-MeO-Butyrfentanyl.
  4. Fentanyls in Europe: A Growing Concern In July 2015, Mounteney, Giraudon, Denissov, and Griffiths highlighted the alarming rise of fentanyls in Europe in “The International Journal on Drug Policy.” Their research underscores the urgent need for monitoring and control.
  5. Swedish STRIDA Project Findings Helander, Bäckberg, and Beck, in April 2016, reported findings from the Swedish STRIDA project, focusing on intoxications involving fentanyl analogs, including acetylfentanyl and 4-methoxybutyrfentanyl. This research enhances our understanding of the dangers associated with these substances.
  6. Narkotika Classification in Sweden In November 2015, the Folkhälsomyndigheten (Public Health Agency of Sweden) reported on “31 nya ämnen kan klassas som narkotika eller hälsofarlig vara” (31 new substances that can be classified as narcotics or hazardous products). This highlights the ongoing efforts to regulate and control emerging synthetic opioids in Sweden.
  7. Controlled Substances Regulation On February 1, 2018, the Federal Register detailed the “Schedules of Controlled Substances: Temporary Placement of Seven Fentanyl-Related Substances in Schedule I.” This regulatory action underscores the need for strict control and regulation of substances related to fentanyl, including 4-MeO-Butyrfentanyl, in the United States.

Leave a Comment

Your email address will not be published. Required fields are marked *