para-Bromoamphetamine

Summary

Parabromoamphetamine (PBA), alternatively referred to as 4-bromoamphetamine (4-BA), belongs to the amphetamine family and functions as a serotonin-norepinephrine-dopamine releasing agent (SNDRA), resulting in stimulant properties.
In addition, there is a closely related compound known as parabromomethamphetamine, identified under the codename V-111.

Identifiers
IUPAC name
CAS Number18455-37-3 
PubChem CID205668
ChemSpider178189 
UNII6IBU62D1N2
ChEMBLChEMBL61355 
CompTox Dashboard (EPA)DTXSID90896914
Chemical and physical data
FormulaC9H12BrN
Molar mass214.106 g·mol−1

Neurotoxicity

Similar to numerous other para-substituted amphetamines, PBA has the potential to be neurotoxic, leading to a potential reduction in 5-hydroxyindoles within the brain for a period lasting at least one week.

FAQ

1. What is para-bromoamphetamine (PBA)?

Para-Bromoamphetamine (PBA) is a chemical compound belonging to the amphetamine class. It acts as a releasing agent for serotonin, norepinephrine, and dopamine, resulting in stimulant effects.

2. Is PBA a recreational drug?

Yes, PBA is sometimes used recreationally for its stimulant properties, although it’s not as widely known or used as other substances.

3. What are the common street names for PBA?

PBA is sometimes referred to as “4-bromoamphetamine” or “4-BA.”

4. How does PBA affect the brain and body?

PBA primarily influences neurotransmitters like serotonin, norepinephrine, and dopamine. It induces stimulant effects, including increased energy, alertness, and a sense of euphoria.

5. What are the potential risks and side effects of PBA use?

Using PBA can be associated with risks, including neurotoxicity and potential depletion of 5-hydroxyindoles in the brain. Users may experience side effects like increased heart rate, anxiety, insomnia, and heightened blood pressure.

6. Is PBA legal?

The legal status of PBA varies by country. In many places, it falls under controlled or regulated substances due to its potential for misuse and health risks.

7. Can PBA be used for medical purposes?

PBA is not approved for medical Use and is primarily encountered in research settings. Its effects and risks make it unsuitable for medical applications.

8. How can I stay safe if I choose to use PBA?

If you decide to use PBA despite the risks, it’s essential to prioritize safety. Use in moderation, be aware of potential side effects, and avoid combining it with other substances. Seek medical help if you experience severe adverse effects.

9. Where can I find more information about PBA?

For comprehensive and up-to-date information about PBA, consult scientific literature, government drug enforcement agencies, or trusted medical sources.

10. Is PBA similar to other amphetamines or stimulants?

PBA shares similarities with other amphetamines in terms of its stimulant effects. However, its specific chemical structure and properties make it distinct from other amphetamines, such as MDMA or methamphetamine. Always exercise caution and awareness when using any substances with stimulant effects.

References

  1. In-depth Insight into p-Bromo-Methylamphetamine (V-111): Magyar K, Tekes K, Zólyomi G, Szüts T, Knoll J. The Metabolism of p-Bromo-Methylamphetamine (V-111) within the Human Body. Acta Physiol Acad Sci Hung. 1981;57(3):285-307. PMID: 7304194.
  2. Comparative Analysis of Amphetamines in Rodents: Fuller RW, Baker JC, Perry KW, Molloy BB (October 1975). “Comparing 4-Chloro, 4-Bromo, and 4-Fluoroamphetamine in Rodents: Concentrations in Brain Tissue and Influence on Brain Serotonin Metabolism.” Neuropharmacology. 14 (10): 739–46. doi:10.1016/0028-3908(75)90099-4. PMID 1196472. S2CID 9620299.

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