Arylcyclohexylamines

3-MeO-PCMo

Summary 3-MeO-PCMo is a dissociative anesthetic drug with structural similarities to phencyclidine (PCP). This substance has been available for purchase online as a designer drug. Notably, its inhibitory effect on the reduction of drebrin cluster density induced by NMDAR stimulation with glutamic acid is comparatively weaker when compared to PCP or 3-MeO-PCP. The half-maximal inhibitory …

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3-MeO-PCE

Summary 3-Methoxyeticyclidine (3-MeO-PCE), also referred to as methoxieticyclidine, is a dissociative anesthetic that shares qualitative similarities with PCE and PCP. It has gained prominence as a designer drug and has been made available through online channels.On October 18, 2012, the Advisory Council on the Misuse of Drugs in the United Kingdom issued a report concerning …

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3-Methyl-PCP

Summary 3-Methyl-PCP, also known as 3′-Methyl-PCP, meta-Methyl-PCP, or 3-Me-PCP, is a designer drug appreciated for its dissociative effects and commonly used for recreational purposes. This compound is a derivative of arylcyclohexylamine and shares chemical connections with substances like 3′-MeO-PCP and 3′-Me-PCPy. Despite its initial synthesis dating back to the 1960s, 3-Methyl-PCP remained off the radar …

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3-HO-PCP

Summary 3-Hydroxyphencyclidine, known as 3-HO-PCP, is a dissociative substance belonging to the arylcyclohexylamine class and is closely related to phencyclidine (PCP). This compound has been available for purchase online as a designer drug. Identifiers IUPAC name CAS Number 79787-43-2 79295-51-5 (hydrochloride) PubChem CID 133277 ChemSpider 117583 UNII V886QLHNA6 CompTox Dashboard (EPA) DTXSID20229918 Chemical and physical data …

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3-Fluoro-PCP

Summary 3-Fluoro-PCP, also known as 3′-F-PCP or 3F-PCP, is a synthetic designer drug belonging to the arylcyclohexylamine family. It is recognized for its dissociative effects, which can lead to altered perceptions and a sense of detachment from reality. This compound was initially discovered in Slovenia in October 2020 and was subject to legal restrictions in …

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3-Chloro-PCP

Summary 3-Chloro-PCP, also known as 3′-Cl-PCP, is a synthetic designer drug classified within the arylcyclohexylamine family. It is renowned for its dissociative effects. While it exhibits potency similar to phencyclidine (PCP), it offers a slightly distinct effects profile. Specifically, it is recognized for its enhanced potency as an NMDA antagonist while maintaining a comparable strength …

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Trifluoromethyldeschloroketamine

Summary Trifluoromethyldeschloroketamine, known as TFMDCK, is a member of the arylcyclohexylamine designer drug category. It is believed to share specific properties with ketamine, a dissociative anesthetic renowned for its hallucinogenic and sedative effects. TFMDCK has been available for purchase on the internet since approximately 2016, although authentic samples seem to be scarce. Additionally, the o-trifluoromethyl …

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Deoxymethoxetamine

Summary Deoxymethoxetamine, also known as 3′-methyl-2-oxo-PCE, DMXE, or 3D-MXE, is a synthetic designer drug classified within the arylcyclohexylamine family, known for its dissociative effects. This substance is a derivative of methoxetamine, with the 3-methoxy group being substituted by a methyl group. It became available for online purchase approximately in October 2020, and a forensic laboratory …

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2-Oxo-PCE

Summary 2-Oxo-PCE, which is also referred to as N-ethyldeschloroketamine, eticyclidone, and O-PCE, is a dissociative anesthetic belonging to the arylcyclohexylamine class. It shares a close structural resemblance with deschloroketamine and eticyclidine and has been available for purchase online as a designer drug. Identifiers IUPAC name CAS Number 6740-82-5 hydrochloride: 4551-92-2  PubChem CID 132989542 ChemSpider 76590394 UNII 2TRF16U3MRhydrochloride: 6Q4N3KH3MG  …

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3-Fluorodeschloroketamine

Summary 3-Fluorodeschloroketamine (often abbreviated as 3F-DCK, 3-FDCK, or FXM) belongs to the family of arylcyclohexylamine designer drugs and is associated with recreational use similar to ketamine. This substance produces dissociative effects. Finland officially prohibited its possession and use in August 2019. Identifiers IUPAC name CAS Number 2657761-23-2 PubChem CID 156538475 Chemical and physical data Formula …

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