Dissociatives

Eticyclidine

Summary Eticyclidine (PCE, CI-400) is a dissociative anesthetic substance renowned for its hallucinogenic properties. It shares similarities in effects with phencyclidine but is marginally more potent. Developed by Parke-Davis during the 1970s, PCE underwent anesthetic evaluation under the codename CI-400. However, research into PCE was discontinued following the emergence of ketamine, a comparable drug with …

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Deschloroketamine

Summary Deschloroketamine (DXE, DCK, 2′-Oxo-PCM) is a dissociative anesthetic compound available through online sources as a designer drug. Additionally, it has been suggested for potential use in the treatment of bacterial, fungal, viral, or protozoal infections, as well as for immunomodulation at a dosage of 2 mg per day. Identifiers IUPAC name CAS Number 7063-30-1 hydrochloride: 4631-27-0  …

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4-MeO-PCP

Summary 4-Methoxyphencyclidine, also known as methoxydine or 4-MeO-PCP, is a dissociative anesthetic drug that has been made available for purchase as a research chemical via online channels. The synthesis of 4-MeO-PCP traces back to 1965 when Victor Maddox, a medicinal chemist at Parke-Davis, first documented its production. In 1999, an anonymous chemist using the pseudonym …

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3-MeO-PCP

Summary 3-Methoxyphencyclidine (3-MeO-PCP) belongs to the arylcyclohexylamine class and is a dissociative hallucinogenic substance closely related to phencyclidine (PCP). It has been available for purchase online as a designer drug. This compound primarily functions as an antagonist of the NMDA receptor. Additionally, it has been observed to interact with the sigma σ1 receptor and the …

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3-MeO-PCMo

Summary 3-MeO-PCMo is a dissociative anesthetic drug with structural similarities to phencyclidine (PCP). This substance has been available for purchase online as a designer drug. Notably, its inhibitory effect on the reduction of drebrin cluster density induced by NMDAR stimulation with glutamic acid is comparatively weaker when compared to PCP or 3-MeO-PCP. The half-maximal inhibitory …

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3-MeO-PCE

Summary 3-Methoxyeticyclidine (3-MeO-PCE), also referred to as methoxieticyclidine, is a dissociative anesthetic that shares qualitative similarities with PCE and PCP. It has gained prominence as a designer drug and has been made available through online channels.On October 18, 2012, the Advisory Council on the Misuse of Drugs in the United Kingdom issued a report concerning …

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3-Methyl-PCPy

Summary 3-Methyl-PCPy, also referred to as 3-Me-PCPy, is a derivative of arylcyclohexylamine known for its unique range of pharmacological effects. Identifiers IUPAC name CAS Number 1622348-63-3  PubChem CID 137332188 UNII FS9Z5C7CQ5 Chemical and physical data Formula C17H25N Molar mass 243.394 g·mol−1 Legal Status 3-Methyl-PCPy falls under drug analog regulations in several jurisdictions, including the UK, Germany, …

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3-Methyl-PCP

Summary 3-Methyl-PCP, also known as 3′-Methyl-PCP, meta-Methyl-PCP, or 3-Me-PCP, is a designer drug appreciated for its dissociative effects and commonly used for recreational purposes. This compound is a derivative of arylcyclohexylamine and shares chemical connections with substances like 3′-MeO-PCP and 3′-Me-PCPy. Despite its initial synthesis dating back to the 1960s, 3-Methyl-PCP remained off the radar …

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3-HO-PCP

Summary 3-Hydroxyphencyclidine, known as 3-HO-PCP, is a dissociative substance belonging to the arylcyclohexylamine class and is closely related to phencyclidine (PCP). This compound has been available for purchase online as a designer drug. Identifiers IUPAC name CAS Number 79787-43-2 79295-51-5 (hydrochloride) PubChem CID 133277 ChemSpider 117583 UNII V886QLHNA6 CompTox Dashboard (EPA) DTXSID20229918 Chemical and physical data …

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3-Fluoro-PCP

Summary 3-Fluoro-PCP, also known as 3′-F-PCP or 3F-PCP, is a synthetic designer drug belonging to the arylcyclohexylamine family. It is recognized for its dissociative effects, which can lead to altered perceptions and a sense of detachment from reality. This compound was initially discovered in Slovenia in October 2020 and was subject to legal restrictions in …

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