FUB-JWH-018, sometimes referred to as FUB-018, is a synthetic cannabinoid derived from naphthoylindole. It can be described as a molecular hybrid, combining elements of JWH-018 and AB-FUBICA or ADB-FUBICA.

IUPAC name
CAS Number2365471-45-8 
Chemical and physical data
Molar mass379.434 g·mol−1

Legal status

In the United States, substances that activate CB1 receptors in the 3-(1-naphthyl)indole class, like FUB-JWH-018, are classified as Schedule I Controlled Substances. Furthermore, as of October 2015, FUB-JWH-018 is regulated as a controlled substance in China.


  • What is FUB-JWH-018?
  • FUB-JWH-018, also known as FUB-018, is a synthetic cannabinoid that falls within the 3-(1-naphthyl)indole class.
  • How does FUB-JWH-018 work?
  • FUB-JWH-018 interacts with cannabinoid receptors, particularly CB1 receptors, in a way that can produce effects similar to those of cannabis.
  • Is FUB-JWH-018 legal in the United States?
  • No, FUB-JWH-018, along with other CB1 receptor agonists of the 3-(1-naphthyl)indole class, is classified as a Schedule I Controlled Substance in the United States, making it illegal.
  • When did FUB-JWH-018 become a controlled substance in China?
  • FUB-JWH-018 was designated as a controlled substance in China as of October 2015.
  • What are the potential effects of FUB-JWH-018?
  • Like other synthetic cannabinoids, FUB-JWH-018 may produce various effects, including altered perception, mood changes, and relaxation. However, these effects can vary among individuals and may carry health risks.
  • Is FUB-JWH-018 safe to use?
  • The safety of FUB-JWH-018 is a subject of concern, and its unregulated nature can lead to unpredictable health risks. It is not approved for medical or recreational use.
  • Are there any legal uses for FUB-JWH-018?
  • FUB-JWH-018 is typically not associated with legal uses, and its production and distribution are often subject to legal restrictions in various countries.
  • Where can I find more information about FUB-JWH-018?
  • For further information, it is advisable to consult reputable sources and adhere to local laws and regulations regarding substances like FUB-JWH-018, which may vary by jurisdiction.


  1. “FUB-JWH 018”: For details about FUB-JWH 018, you can refer to information provided by Cayman Chemical, retrieved on July 8, 2015.
  2. Lamoureux C (June 2015): In June 2015, a study by Lamoureux explored the utilization of a high-resolution quadrupole time-of-flight (HR-Q-TOF) mass spectrometer for identifying new psychoactive substances in circulation. This research was published in Toxicologie Analytique et Clinique, Volume 27, Issue 2.
  3. 21 U.S.C. § 812: The United States Code (21 U.S.C.) in Section 812 outlines the Schedules of controlled substances in the United States, providing the legal framework for the regulation of various substances.
  4. “关于印发《非药用类麻醉药品和精神药品列管办法》的通知 (in Chinese)”: This Chinese notification from the China Food and Drug Administration, dated September 27, 2015, discusses regulations concerning non-medicinal narcotic drugs and psychotropic drugs, with an archived version available until October 1, 2015.

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