Dipyanone, an opioid analgesic, emerged as a designer drug and was initially detected in Germany in 2021. This compound shares close structural similarities with medically approved opioids like methadone, dipipanone, and phenadoxone, although it exhibits slightly less potency.

IUPAC name
CAS Number60996-94-3 
Chemical and physical data
Molar mass335.491 g·mol−1


  • What is Dipyanone?
  • Dipyanone is an opioid analgesic, which is a type of pain-relief medication. It was initially identified as a designer drug in Germany in 2021.
  • How does Dipyanone work?
  • Like other opioids, Dipyanone works by binding to opioid receptors in the brain and spinal cord, which results in a reduction in the perception of pain.
  • Is Dipyanone approved for medical use?
  • As of my last knowledge update in September 2021, Dipyanone had not been approved for medical use in most countries. It was primarily recognized as a designer drug.
  • How does Dipyanone compare to other opioids?
  • Dipyanone shares structural similarities with medically approved opioids such as methadone, dipipanone, and phenadoxone. However, it is generally considered to be slightly less potent.
  • What are the risks associated with Dipyanone use?
  • The use of Dipyanone, like other opioids, carries significant risks, including the potential for respiratory depression, sedation, addiction, and overdose. It should be used under the guidance of a healthcare professional.
  • Is Dipyanone legal to possess or use?
  • The legal status of Dipyanone may vary by country and is subject to change over time. It’s essential to be aware of the local regulations and laws regarding this substance in your area.
  • Is there any known medical application for Dipyanone?
  • As of my last knowledge update, Dipyanone had not been approved for any medical applications. It was primarily associated with the recreational or designer drug market.
  • Is Dipyanone available online as a designer drug?
  • Dipyanone has been reported as being available online as a designer drug in some regions. However, it’s essential to exercise caution when dealing with such substances, as their quality and legality can be uncertain.
  • What precautions should one take if they encounter Dipyanone?
  • If you come across Dipyanone or products claiming to contain it, exercise extreme caution. Given the potential risks and uncertainties surrounding its authenticity and legality, it’s advisable to avoid using it. Consult with a healthcare professional if you have any concerns or questions about this substance.


  1. European Monitoring Centre’s Insight (June 2022): In June 2022, the European Monitoring Centre for Drugs and Drug Addiction provided a comprehensive report titled “New Psychoactive Substances: 25 Years of Early Warning and Response in Europe.” This publication serves as an update from the EU Early Warning System and is available in PDF format. You can access it via the DOI: 10.2810/882318, and it bears the ISBN 978-92-9497-737-3.
  2. Exploring Amidone Variations (1950): A noteworthy scientific exploration occurred in 1950 when Ofner P and Walton E embarked on research in the pursuit of new analgesics. Their work, documented as “Search for New Analgesics. Part IV. Variations in the Basic Side-Chain of Amidone,” was published in the Journal of the Chemical Society (Resumed), specifically on page 2158. Their research can be accessed via DOI: 10.1039/JR9500002158.
  3. Opiates: Insights and Perspectives (1986): In 1986, a significant academic resource was published under the title “Opiates.” This work, authored by Lenz GR, Evans SM, Walters DE, and Hopfinger AJ, offers in-depth insights into the world of opiates. The book spans across pages 406 to 407 and is cataloged under ISBN 978-0-12-443830-9. It remains a valuable reference in the field of opiate research.

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