1P-ETH-LAD, scientifically known as 1-propionyl-6-ethyl-6-nor-lysergic acid diethylamide, is an analog of LSD (lysergic acid diethylamide). This psychedelic compound shares similarities with LSD and belongs to the lysergamide chemical class. Research has indicated that 1P-ETH-LAD can undergo a conversion to ETH-LAD when incubated in human serum, suggesting it may function as a prodrug. Notably, like ETH-LAD, 1P-ETH-LAD is reported to be significantly more potent than LSD and is said to replicate ETH-LAD’s psychedelic effects closely.
It’s noteworthy that 1P-ETH-LAD had limited documented human usage before January 2016.

IUPAC name
PubChem CID119025859
Chemical and physical data
Molar mass393.531 g·mol−1

Legal issues

United States: The use of 1P-ETH-LAD for human consumption may fall under the scope of the Federal Analogue Act in the United States, potentially rendering it illegal.

United Kingdom: The production, supply, or importation of this substance is prohibited in the United Kingdom under the Psychoactive Substance Act, which became effective on May 26, 2016.


1. What is 1P-ETH-LAD?

  • 1P-ETH-LAD, or 1-propionyl-6-ethyl-6-nor-lysergic acid diethylamide, is a chemical compound similar to LSD (lysergic acid diethylamide). It is known for its psychedelic properties.

2. Is 1P-ETH-LAD legal?

  • The legal status of 1P-ETH-LAD varies by country. It may be considered illegal in some places, while in others, it may exist in a legal gray area. Checking local laws and regulations regarding its possession, sale, or use is crucial.

3. How does 1P-ETH-LAD compare to LSD?

  • 1P-ETH-LAD is an analog of LSD, and both substances share similarities in their effects. However, 1P-ETH-LAD is reported to be significantly more potent than LSD and may closely mimic the psychedelic impacts of ETH-LAD.

4. Is 1P-ETH-LAD a prodrug for ETH-LAD?

  • Research has suggested that 1P-ETH-LAD can function as a prodrug, leading to ETH-LAD formation when incubated in human serum. This conversion may influence the nature and duration of its psychedelic effects.

5. What are the reported effects of 1P-ETH-LAD?

  • Like LSD and other lysergamides, 1P-ETH-LAD induces psychedelic effects, including alterations in perception, mood, and consciousness. Users may experience visual distortions, enhanced sensory perception, and changes in thought patterns.

6. What is the legal status of 1P-ETH-LAD in the United States?

  • In the United States, the legal status of 1P-ETH-LAD may be subject to the Federal Analogue Act, which means it could be considered illegal for human consumption.

7. Is 1P-ETH-LAD legal in the United Kingdom?

  • In the United Kingdom, the production, supply, or importation of 1P-ETH-LAD is illegal under the Psychoactive Substance Act, which came into effect on May 26, 2016.

8. Does 1P-ETH-LAD have a history of human use?

  • 1P-ETH-LAD had limited documented human usage before January 2016, and its use and effects are still being studied.

9. Where can I obtain 1P-ETH-LAD for research purposes?

  • The availability of 1P-ETH-LAD may vary by region and local regulations. Researchers typically source it from reputable chemical suppliers that cater to scientific research needs, always adhering to applicable laws and guidelines.

10. Are there potential therapeutic applications for 1P-ETH-LAD?

– There is limited research on the therapeutic potential of 1P-ETH-LAD. Like other psychedelics, it is being explored for potential applications in mental health and psychotherapy, but more studies are needed to determine its efficacy and safety.

Please note that 1P-ETH-LAD, like all psychoactive substances, should be approached cautiously, and responsible use and adherence to local laws and regulations are crucial. Consulting with professionals and following safety guidelines is essential to minimize risks.


  1. “Arrêté du 20 mai 2021 amendant l’arrêté du 22 février 1990 établissant la liste des substances classées comme stupéfiants.” Retrieved from www.legifrance.gouv.fr (in French) on May 20, 2021.
  2. Brandt SD, Kavanagh PV, Westphal F, Elliott SP, Wallach J, Stratford A, et al. (October 2017). “6-ethyl-6-norlysergic acid diethylamide (ETH-LAD) and 1-propionyl ETH-LAD (1P-ETH-LAD).” Drug Testing and Analysis. 9 (10): 1641–1649. doi:10.1002/dta.2196. PMC 6230477. PMID 28342178.
  3. “Psychoactive Substances Act 2016.” Retrieved from Legislation.gov.uk.

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