Summary
2,5-Dimethoxy-4-propylamphetamine (DOPR) belongs to the phenethylamine and amphetamine chemical classes and was initially synthesized by Alexander Shulgin. Shulgin introduced this compound in his renowned work, “PiHKAL” (Phenethylamines I Have Known And Loved). DOPR, according to Shulgin, is a profoundly potent psychedelic substance capable of inducing substantial alterations in thought processes and significant visual distortions.
Regrettably, there is a lack of information regarding the pharmacological properties, metabolic processes, and potential toxicity associated with DOPR.
An alternative structural isomer, known as DOIP (which features a 4-isopropyl substitution), also exists but is notably less potent than DOPR, requiring a significantly higher active dose of approximately 20–30 mg in contrast to the 2–5 mg needed for DOPR.
| Identifiers | |
|---|---|
| IUPAC name | |
| CAS Number | 63779-88-4 53581-55-8 (hydrochloride) |
|---|---|
| PubChem CID | 542051 |
| ChemSpider | 472021 |
| UNII | L3P287BI9W |
| ChEMBL | ChEMBL8569 |
| CompTox Dashboard (EPA) | DTXSID40337347 |
| Chemical and physical data | |
| Formula | C14H23NO2 |
| Molar mass | 237.343 g·mol−1 |
FAQ
- What is 2,5-Dimethoxy-4-propylamphetamine (DOPR)?
- DOPR is a psychedelic compound in the phenethylamine and amphetamine chemical classes. It’s known for its mind-altering properties.
- Who first synthesized DOPR, and where can I find more information about it?
- DOPR was first synthesized by Alexander Shulgin and is described in his book “PiHKAL” (Phenethylamines I Have Known And Loved). You can find more details about DOPR in this book.
- How does DOPR affect the mind and perception?
- DOPR is described as a “heavy-duty psychedelic” by Shulgin. It can lead to significant alterations in thought processes and induce visual distortions.
- Is DOPR safe to use?
- The safety of DOPR use is not well-documented, and it is considered a powerful psychedelic. It can lead to intense and potentially unpredictable experiences. Using DOPR can be risky and is generally discouraged.
- What are the risks associated with DOPR use?
- Risks include hallucinations, disorientation, and potentially harmful behavior. In high doses, it may also pose physical health risks.
- Is DOPR addictive?
- DOPR is not typically considered physically addictive. However, like other psychedelics, it can be psychologically habit-forming in some individuals.
- What is the alternative isomer DOIP, and how does it compare to DOPR?
- DOIP is a structural isomer of DOPR with a 4-isopropyl substitution. It is significantly less potent than DOPR, requiring a much higher dose (around 20–30 mg compared to 2–5 mg for DOPR) to achieve similar effects.
- Where can I find more information about the pharmacological properties, metabolism, and toxicity of DOPR?
- Unfortunately, very little data exists on these aspects of DOPR. You should exercise caution and seek information from reputable sources to explore this substance.
- Is DOPR legal in the United States and other countries?
- The legal status of DOPR varies by country and region. It’s essential to research and understand the laws and regulations regarding its use and possession in your area.
- How can I ensure safety when using DOPR or similar substances?
- Prioritize safety by being well-informed, using harm reduction practices, and seeking guidance from healthcare professionals or harm reduction organizations. Always be aware of the legal status and potential risks associated with the substance.
References
- Shulgin A, Shulgin A (September 1991). PiHKAL: A Chemical Love Story. United States: Transform Press. p. 978. ISBN0-9630096-0-5.