Summary 3,4-Methylenedioxy-N-hydroxyamphetamine, MDOH or MDH, belongs to the entactogen, psychedelic, and stimulant categories within the phenethylamine and amphetamine chemical families. This compound serves as the N-hydroxy counterpart of MDA and the N-desmethyl analog of MDHMA. Alexander Shulgin carried out the initial synthesis and evaluation of MDOH.In his influential book, “PiHKAL” (Phenethylamines I Have Known And …
Summary N-Methyl-1,3-benzodioxolylpentanamine (MBDP; also referred to as Methyl-K, UWA-091), scientifically known as 3,4-methylenedioxy-α-propyl-N-methylphenethylamine, is a psychoactive compound belonging to the phenethylamine chemical class. This substance is the N-methyl counterpart to 1,3-benzodioxolylpentanamine (BDP; K). Methyl-K synthesis can be credited to Alexander Shulgin, often affectionately called “Sasha” Shulgin. Shulgin’s comprehensive work, PiHKAL (“Phenethylamines I Have Known And …
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Summary 3,4-Methylenedioxy-N-ethylamphetamine (MDEA) is a psychoactive drug with empathogenic properties, sometimes referred to as MDE or colloquially known as Eve. It falls into the category of substituted amphetamines and substituted methylenedioxyphenethylamines. MDEA is a substance that releases and inhibits the reuptake of serotonin, norepinephrine, and dopamine in the brain.It’s important to note that the possession …
Summary 3,4-Methylenedioxy-N-hydroxyamphetamine (MDOH), also known as MDH or N-hydroxytenamphetamine, is a compound that falls into the categories of entactogen, psychedelic, and stimulant. It belongs to the phenethylamine and amphetamine chemical classes. MDOH is the N-hydroxy counterpart of MDA and the N-desmethyl counterpart of MDHMA.This compound was initially synthesized and evaluated by Alexander Shulgin. In his …
Summary Ethylone, or 3,4-methylenedioxy-N-ethylcathinone (MDEC or βk-MDEA), is a recreational designer drug with classifications in the entactogen, stimulant, and psychedelic categories. It belongs to the phenethylamine, amphetamine, and cathinone chemical classes. Ethylone serves as the β-keto analog of MDEA, commonly known as “Eve.” Notably, it has a relatively brief history of human use and is …
Summary Ethylbenzodioxolylbutanamine (EBDB), also known as Ethyl-J, is a relatively lesser-known substance known for its entactogenic, stimulant, and psychedelic properties. It serves as the N-ethyl counterpart to benzodioxylbutanamine (BDB), often referred to as “J,” and the α-ethyl companion to methylenedioxymethamphetamine (MDEA), commonly known as “Eve.”Alexander Shulgin first carried out the synthesis of EBDB. In his …
Summary Dimethylone, or βk-MDDMA, belongs to the substituted cathinone class and possesses stimulant and empathogenic properties. Unlike its amphetamine counterpart, MDDM, which is believed to have little to no activity, dimethylone has demonstrated its ability to substitute for methamphetamine and MDMA in animal studies. Consequently, it has been marketed and sold as a designer drug. …
Summary Dibutylone, or bk-DMBDB, falls within the stimulant drug category, encompassing the amphetamine, phenethylamine, and cathinone classes. Its chemical structure resembles butylone, another designer drug often found in products sold as bath salts or plant food.Notably, in 2018, dibutylone emerged as the third most frequently encountered cathinone-class drug in seizures conducted by the Drug Enforcement …
Summary Butylone, alternatively referred to as β-keto-N-methylbenzodioxolylbutanamine (βk-MBDB), is a psychoactive substance belonging to the phenethylamine chemical class. It possesses entactogenic, psychedelic, and stimulant properties. Butylone is recognized as the β-keto derivative, akin to substituted cathinone, of MBDB, and it serves as the substituted methylenedioxyphenethylamine analog of buphedrone. Identifiers IUPAC name CAS Number 802575-11-7 PubChem …
Summary 3-Fluoroethamphetamine (3-FEA) is a stimulant categorized within the amphetamine class. It is a releasing agent for the monoamine neurotransmitters, including norepinephrine, dopamine, and serotonin.Compared to the non-substituted ethylamphetamine, 3-fluoroethamphetamine exhibits reduced potency in releasing noradrenaline. However, it demonstrates greater efficacy in releasing both dopamine and serotonin. Interestingly, in animal studies comparing various 3-substituted methamphetamine …
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