In the world of designer drugs and research chemicals, consumers are often confronted with the challenging task of identifying reputable vendors for their purchases. Βk-2C-B, a synthetic compound similar to the psychedelic 2C-B, has gained attention as one of these substances. However, the availability of Βk-2C-B for sale online has raised concerns about the reliability and safety of the vendors involved.
First and foremost, potential buyers of Βk-2C-B should exercise extreme caution when searching for online sellers. The unregulated nature of the research chemical market means that not all vendors prioritize quality and safety. Some may be more interested in profit than the well-being of their customers. To avoid disappointment or potential harm, thorough research on vendors is crucial.
Legitimate Βk-2C-B research chemical sellers should provide transparency in their operations. This includes disclosing the source of their product, adhering to ethical manufacturing processes, and maintaining stringent quality control measures. Unfortunately, not all vendors meet these standards. Some may sell adulterated or impure Βk-2C-B, putting consumers at risk of unexpected and potentially dangerous side effects.
Moreover, it is essential for buyers to consider the legal implications of their purchase. Laws regarding research chemicals and designer drugs can vary widely by region and country. Purchasing Βk-2C-B from an online vendor may expose buyers to legal consequences, especially if the substance is banned in their location.
- 1 Summary
- 2 History and culture
- 3 Chemistry
- 4 Pharmacology
- 5 Subjective effects
- 6 Toxicity
- 7 Legal status
- 8 FAQ
- 8.1 1. What is βk-2C-B?
- 8.2 2. What are the subjective effects of βk-2C-B?
- 8.3 3. Is βk-2C-B safe to use?
- 8.4 4. Is βk-2C-B legal?
- 8.5 5. Can βk-2C-B be addictive?
- 8.6 6. How long does it take for tolerance to βk-2C-B to reset?
- 8.7 7. Are there any known health risks associated with βk-2C-B?
- 8.8 8. How should I approach using βk-2C-B?
- 8.9 9. Is βk-2C-B similar to 2C-B in its effects?
- 9 References
βk-2C-B, also known as Bk-2C-B or beta-keto 2C-B, is a fresh addition to the psychedelic spectrum within the phenethylamine class. This compound shares a structural resemblance to the well-known psychedelic 2C-B.
Subjective experiences reported by users encompass a range of effects, including both open and closed-eye visuals, alterations in time perception, heightened euphoria, and even episodes of ego dissolution. Notably, when compared to 2C-B, βk-2C-B exhibits heightened stimulating properties while veering towards a less pronounced psychedelic character, coupled with an extended duration of action.
It’s important to note that βk-2C-B remains relatively uncommon, boasting little to no historical record of human usage before its emergence in 2014, when it was distributed by online vendors specifically for research purposes.
The body of knowledge concerning the pharmacological attributes, metabolic pathways, and potential toxicity of βk-2C-B remains severely limited. Consequently, individuals considering its use are strongly advised to approach this novel, poorly understood hallucinogenic substance with utmost caution and dedication to harm reduction practices. Given the absence of comprehensive data, responsible and informed decision-making becomes paramount for those who explore the effects of βk-2C-B.
|show IUPAC name|
|Chemical and physical data|
|Molar mass||274.111 g/mol (freebase)|
310.572 g/mol (HCl salt) g·mol−1
History and culture
The original synthesis of βk-2C-B remains undocumented in the public domain. Contrary to many 2C-x compounds attributed to Alexander Shulgin’s work in the 1970s, it appears that βk-2C-B did not originate from his research.
The first credible reference to βk-2C-B emerged in 2004 when it played a minor role in a scientific investigation as a precursor to 5-HT2A serotonin receptor agonists. However, the substance remained relatively obscure until December 2007 when a user named “King Kong” initiated a discussion thread on the bluelight.org forum dedicated to gathering information and facilitating discourse about βk-2C-B. There was brief speculation about the molecule’s stability, but the thread garnered no more than 20 posts over the following six years.
βk-2C-B began to gain more recognition around 2013. This coincided with the first firsthand experience reports on the internet, closely following its introduction to the research chemical market via “online head shops.” It was marketed as a “legal replacement for 2C-B.”
Despite these developments, βk-2C-B remains relatively obscure, even within research chemicals. An analysis of Google search trends from 2013 to 2017 reveals that searches for 2C-B consistently outnumbered those for βk-2C-B by a ratio of 3 to 4. Since 2017, βk-2C-B seems to have largely disappeared from the open market, further contributing to its enigmatic status.
βk-2C-B, also known as beta-keto 2C-B, falls under substituted phenethylamines. It is characterized by a phenyl ring linked to an amino (NH2) group via an ethyl chain. In its chemical structure, βk-2C-B features a ketone group at the beta carbon (R1) of the 2C-B framework. Additionally, this compound bears methoxy functional groups (CH3O-) attached to carbons R2 and R5, along with a bromine atom affixed to carbon R4 within the phenyl ring. βk-2C-B belongs to the 2C family of phenethylamines, characterized by methoxy groups at the 2 and 5 positions of the benzene ring.
Βk-2C-B probably functions as a partial agonist of the 5-HT2A receptor. The psychedelic effects of this compound stem from its activity at the 5-HT2A receptors. Nevertheless, the precise mechanisms underlying these interactions and their contribution to the psychedelic encounter remain poorly understood and elusive.
Disclaimer: The effects detailed below are derived from the Subjective Effect Index (SEI), which relies on anecdotal user accounts and the personal assessments of contributors at PsychonautWiki. Consequently, a healthy dose of skepticism should accompany their consideration.
It is essential to acknowledge that these effects may not manifest predictably or consistently. However, higher doses are more likely to encompass the complete spectrum of effects. Moreover, as doses increase, the probability of adverse effects escalates, potentially including addiction, severe harm, or even fatality ☠.
- Spontaneous tactile sensations
- Elevated heart rate
- Pupil dilation
- Amplified perception of colors
- Heightened pattern recognition
- Enhanced visual clarity
- Visual drifting (objects appearing to melt, breathe, morph, or flow)
- Shifting of colors
- Distorted depth perception
- Altered perspective
- Symmetrical texture repetition
- Changes in brightness perception
- Geometric patterns
- Hallucinatory experiences
- Internal hallucinations (featuring autonomous entities, vivid settings, landscapes, altered perspectives, scenarios, and plots)
- Conceptual thinking
- Cognitive euphoria
- Enhanced emotions
- Increased immersion in experiences
- Elevated appreciation of music
- Suppressed memory recall
- Ego dissolution
- Heightened novelty perception
- Reduced personal bias
- Thought loops
- Time distortion
- A sense of unity and interconnectedness
- Auditory perception amplification
- Auditory hallucinations
The toxicity and potential long-term health consequences associated with recreational βk-2C-B use have not undergone comprehensive scientific investigation, and the precise toxic dosage remains undisclosed. This is primarily due to βk-2C-B’s status as a research chemical with minimal historical human consumption records. Anecdotal insights shared by members of the psychonaut community who have experimented with βk-2C-B suggest that, when used in isolation and at low to moderate doses, the substance does not appear to produce adverse health effects. However, guarantees cannot be provided. It is strongly emphasized that thorough individual research should precede the consumption of any combination of two or more substances to ensure safety.
The practice of harm reduction is highly recommended when using this substance.
Tolerance and potential for addiction:
Similar to most psychedelics, βk-2C-B is not associated with habit formation, and in fact, the desire to use it may diminish with continued use. Typically, it self-regulates.
Tolerance to the effects of βk-2C-B develops almost immediately following ingestion. Subsequently, it takes approximately three days for the tolerance to decrease by half and seven days to return to baseline levels, provided there is no further consumption. It is noteworthy that βk-2C-B induces cross-tolerance with all psychedelics, meaning that its consumption of βk-2C-B will diminish other psychedelics’ impact.
Canada: As of October 12, 2016, βk-2C-B has been categorized as a Schedule III controlled substance.
Germany: βk-2C-B falls under the regulations of the NpSG (New Psychoactive Substances Act) on November 26, 2016. Activities such as production, importation for distribution, administering to others, and trading are subject to legal penalties. Possession, while illegal, is not met with punitive measures.
Japan: As of March 25, 2015, βk-2C-B is designated as a controlled substance in Japan.
Switzerland: βk-2C-B is listed as a controlled substance under Verzeichnis E in Switzerland.
Sweden: On April 5, 2019, βk-2C-B was classified as a narcotic in Sweden.
United Kingdom: The production, distribution, or importation of this substance is illegal in the United Kingdom under the Psychoactive Substance Act, which was enacted on May 26, 2016.
United States: In the United States, βk-2C-B is not scheduled, but it may be considered an analog of 2C-B according to the Federal Analogue Act, potentially resulting in classification as a Schedule I drug.
1. What is βk-2C-B?
βk-2C-B, or beta-keto 2C-B, is a synthetic compound in the phenethylamine class. It is structurally related to the psychedelic 2C-B.
2. What are the subjective effects of βk-2C-B?
The subjective effects of βk-2C-B may include open and closed-eye visuals, time distortion, euphoria, and even ego loss. It is important to note that individual experiences may vary.
3. Is βk-2C-B safe to use?
The safety of βk-2C-B is not well-established. Due to its status as a research chemical and limited scientific research, the risks associated with its use are not fully understood. Caution and harm reduction practices are strongly advised.
4. Is βk-2C-B legal?
The legal status of βk-2C-B varies by country. It is essential to check the specific laws and regulations in your region. In some countries, it may be a controlled substance.
5. Can βk-2C-B be addictive?
βk-2C-B is generally not considered habit-forming, and the desire to use it may decrease with continued use.
6. How long does it take for tolerance to βk-2C-B to reset?
Tolerance to βk-2C-B builds quickly after ingestion. Typically, it takes about three days for the tolerance to decrease by half and seven days to return to baseline if no further consumption occurs.
7. Are there any known health risks associated with βk-2C-B?
The long-term health effects and toxicity of βk-2C-B are not well-studied scientifically. Adverse effects become more likely with higher doses and may include severe harm. Always exercise caution and conduct thorough research before using this substance.
8. How should I approach using βk-2C-B?
If you choose to use βk-2C-B, it is essential to approach it with caution. Start with low to moderate doses and use harm-reduction practices. Ensure you are well informed about the substance and its potential risks.
9. Is βk-2C-B similar to 2C-B in its effects?
While βk-2C-B shares structural similarities with 2C-B, user reports suggest its effects may differ. βk-2C-B is often described as more stimulating and less psychedelic than 2C-B, with a longer duration.
- In a study published in June 2015, Power, J. D., Kavanagh, P., O’Brien, J., Barry, M., Twamley, B., Talbot, B., Dowling, G., and Brandt, S. D. conducted research on “Test purchase, identification and synthesis of 2‐amino‐1‐(4‐bromo‐2, 5‐dimethoxyphenyl)ethan‐1‐one (bk‐2C‐B)” in the journal Drug Testing and Analysis (Vol. 7, No. 6, pp. 512–518). They delved into the identification and synthesis of this compound, contributing to the understanding of designer drugs. [DOI: 10.1002/dta.1699]
- Frison, G., Odoardi, S., Frasson, S., Sciarrone, R., Ortar, G., Romolo, F. S., and Strano Rossi, S. published their findings in a study on “Characterization of the designer drug bk-2C-B (2-amino-1-(bromo-dimethoxyphenyl)ethan-1-one)” in the journal Rapid Communications in Mass Spectrometry: RCM (Vol. 29, No. 13, pp. 1196–1204) in July 2015. Their research included gas chromatography/mass spectrometry analysis and nuclear magnetic resonance, shedding light on this emerging psychoactive substance. [DOI: 10.1002/rcm.7211]
- Glennon, R. A., Bondarev, M. L., Khorana, N., Young, R., May, J. A., Hellberg, M. R., McLaughlin, M. A., and Sharif, N. A. explored “Beta-oxygenated analogs of the 5-HT2A serotonin receptor agonist 1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane” in the Journal of Medicinal Chemistry (Vol. 47, No. 24, pp. 6034–6041) in November 2004. Their research focused on compounds related to bk-2C-B and their impact on serotonin receptors. [DOI: 10.1021/jm040082s]
- The online forum “Bluelight.ru” featured a discussion titled “The Big & Dandy βK-2C-B Thread – Part 1,” where users exchanged information and experiences related to bk-2C-B. [Link: https://www.bluelight.org/xf/threads/the-big-dandy-%CE%B2k-2c-b-thread-part-1.694585]
- Beharry, S., and Gibbons, S. provided an overview of emerging psychoactive substances, including bk-2C-B, in the United Kingdom in their study published in Forensic Science International (Vol. 267, pp. 25–34) in October 2016. This research highlighted the presence and challenges posed by new psychoactive substances in the UK. [DOI: 10.1016/j.forsciint.2016.08.013]
- The status of bk-2C-B was last checked in September 2020 via Google Scholar [Link: https://scholar.google.de/scholar?hl=de&as_sdt=0%2C5&q=%22bk-2c-b%22&btnG=&oq=%22bk-2c-%22] and Google Trends [Link: https://trends.google.com/trends/explore?date=all&q=%CE%B2k-2C-B,%22bk-2C-B%22,%222C-B%22] to monitor its research presence and online interest.
- “Gesetz zur Bekämpfung der Verbreitung neuer psychoaktiver Stoffe” (Law to Combat the Distribution of New Psychoactive Substances) in German was retrieved from Bundesanzeiger Verlag on December 11, 2019.
- “Anlage NpSG” (Annex to the Law on New Psychoactive Substances) in German was obtained from Bundesministerium der Justiz und für Verbraucherschutz on December 11, 2019.
- “§ 4 NpSG” (Section 4 of the Law on New Psychoactive Substances) in German was retrieved from Bundesministerium der Justiz und für Verbraucherschutz on December 11, 2019.
- The Ministry of Health, Labour and Welfare (MHLW) designated 16 substances, including bk-2C-B, as specified drugs in Japan. This decision was reported in the Japanese language as “危険ドラッグの成分１６物質を新たに指定薬物に指定” and dated May 2, 2022.
- “Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien” (Ordinance of the Federal Chancellery of Switzerland on the Lists of Narcotic Substances, Psychotropic Substances, Precursor Substances, and Auxiliary Chemicals) in German was retrieved on January 1, 2020.
- In Sweden, the Swedish Public Health Agency (Folkhälsomyndigheten) classified eight new substances, one of which is bk-2C-B, as narcotics. This announcement was made in the Northern Sami language as “Åtta nya ämnen klassas som narkotika” on January 4, 2021.
- The Psychoactive Substances Act of 2016 is a UK legislation that addresses the regulation of psychoactive substances, including those like bk-2C-B and was enacted to combat their distribution and use.