Methamphetamine, often marketed as a research chemical or designer drug, has been the subject of growing concern due to its availability for purchase online from various sellers. A critical review of these online vendors reveals several alarming issues.
Firstly, the sale of Methamphetamine as a research chemical highlights a concerning trend in the designer drug market. While some individuals may genuinely purchase it for scientific research, most buyers are likely seeking it for recreational use. This misuse of research chemicals poses substantial health risks, as these substances’ effects and long-term consequences are often poorly understood.
Moreover, the quality and safety of Methamphetamine purchased from online sellers are questionable. These products often lack proper quality control, accurate labeling, and safety guidelines. Researchers relying on these sources may unknowingly expose themselves to substances with unverified compositions and potentially dangerous contaminants.
The proliferation of Methamphetamine online vendors also contributes to a thriving black market. This not only fuels the illicit drug trade but also makes it challenging for authorities to regulate and control the distribution of such substances.
Furthermore, the lack of proper education and harm reduction measures associated with selling Methamphetamine online exacerbates the dangers. Users often lack crucial information about dosing, potential side effects, and interactions with other substances.
- 1 SUMMARY
- 2 Legal status
- 3 FAQ
- 3.1 1. What is Methamnetamine?
- 3.2 2. How is Methamnetamine different from methamphetamine?
- 3.3 3. What are the neurotransmitters affected by Methamnetamine?
- 3.4 4. Is Methamnetamine available for purchase online?
- 3.5 5. Are there any known health risks associated with Methamnetamine use?
- 3.6 6. Is Methamnetamine legal in all regions?
- 3.7 7. Can Methamnetamine be detected in drug tests?
- 3.8 8. Is Methamnetamine considered a controlled substance?
- 4 References
Methamphetamine, or methylamphetamine, MNA, MNT, and PAL-1046, is a compound with properties as a triple monoamine-releasing agent. It serves as the N-methyl counterpart to the non-neurotoxic experimental substance naphthylaminopropane and is the naphthalene-based analog of methamphetamine. This compound has gained attention as a designer drug and is available online.
Regarding its pharmacological effects, Methamnetamine is a potent releasing agent for three important neurotransmitters: serotonin, norepinephrine, and dopamine. The EC50 values for its action on these neurotransmitters are 13 nM, 34 nM, and 10 nM, respectively.
|Legal status||DE: NpSG (Industrial and scientific use only) UK: Under Psychoactive Substances ActIllegal in Japan|
1. What is Methamnetamine?
- Methamnetamine, known as methylnaphetamine, MNA, MNT, and PAL-1046, is a chemical compound with triple monoamine-releasing agent properties. It is structurally related to methamphetamine and has gained attention as a designer drug.
2. How is Methamnetamine different from methamphetamine?
- Methamnetamine is a naphthalene analog of methamphetamine and serves as the N-methyl counterpart to naphthylaminopropane. While both substances affect monoamine neurotransmitters, they have different chemical structures and potentially distinct bodily effects.
3. What are the neurotransmitters affected by Methamnetamine?
- Methamnetamine acts as a releasing agent for three important neurotransmitters: serotonin, norepinephrine, and dopamine. It has specific EC50 values for each neurotransmitter, indicating its potency in affecting its release.
4. Is Methamnetamine available for purchase online?
- Yes, Methamnetamine has been sold online as a designer drug. However, its legal status may vary by location, and it is essential to be aware of local regulations and restrictions regarding its sale and possession.
5. Are there any known health risks associated with Methamnetamine use?
- Methamnetamine, like other designer drugs, carries potential health risks. These risks may include adverse effects on the cardiovascular system, mental health, and overall well-being. Additionally, the long-term effects and safety profile of Methamnetamine are not well-studied.
6. Is Methamnetamine legal in all regions?
- The legality of Methamnetamine varies by country and jurisdiction. Researching and understanding the specific laws and regulations regarding this substance in your area is crucial.
7. Can Methamnetamine be detected in drug tests?
- Methamnetamine may not be specifically tested for in standard drug tests. However, its use may still produce a positive test for amphetamines due to its structural similarity to methamphetamine.
8. Is Methamnetamine considered a controlled substance?
- The classification of Methamnetamine as a controlled substance also varies by location. It is advisable to check with local authorities or drug enforcement agencies to determine its legal status in your area.
- Rothman RB, Partilla JS, Baumann MH, Lightfoot-Siordia C, Blough BE (April 2012). “Studies of the biogenic amine transporters. 14. Identification of low-efficacy “partial” substrates for the biogenic amine transporters.” The Journal of Pharmacology and Experimental Therapeutics. 341 (1): 251–262. doi:10.1124/jpet.111.188946. PMC 3364510. PMID 22271821.
- Youn DH, Kim JM, Hong YK, Park SI, Lee JM, Kim YH, et al. (August 2021). “Assessment of the abuse potential of methamphetamine in rodents: a behavioral pharmacology study.” Psychopharmacology. 238 (8): 2155–2165. doi:10.1007/s00213-021-05840-9. PMID 33811503. S2CID 232773019.
- Hong YK, Kim YH, Lee JM, Yoo HH, Choi SO, Kang MS (July 2021). “Characterization of in vitro phase I metabolites of methamnetamine in human liver microsomes by liquid chromatography-quadrupole time-of-flight mass spectrometry.” International Journal of Legal Medicine. 135 (4): 1471–1476. doi:10.1007/s00414-021-02594-z. PMID 33928430. S2CID 233451101.
- “Methamnetamine”. WEDINOS.
- “Methamnetamine”. New Synthetic Drugs Database.
- “指定薬物名称・構造式一覧（平成27年9月16日現在）” [List of designated drug names and structural formulas (as of September 16, 2015)] (PDF). 厚生労働省 [Ministry of Health, Labour and Welfare] (in Japanese). September 16, 2015. Retrieved October 8, 2015.