Isoproscaline

Summary

Isoproscaline, scientifically known as 4-isopropoxy-3,5-dimethoxyphenethylamine, is an analog of mescaline. This compound shared a close kinship with prescaling and was initially synthesized by David E. Nichols, although specific sourcing details might require citation.
Isoproscaline is renowned for its capacity to induce hallucinogenic, psychedelic, and entheogenic effects.

Identifiers
CAS Number64778-72-9 
3D model (JSmol)Interactive image
ChEMBLChEMBL126203 
ChemSpider10439597 
PubChemCID15102787
UNII7W67II88GC 
CompTox Dashboard(EPA)DTXSID70215088
SMILES
Properties
Chemical formulaC13H21NO3
Molar mass239.31 g/mol

Chemistry

Isoproscaline belongs to the category of compounds commonly referred to as phenethylamines. Its complete chemical nomenclature is 2-(4-isopropoxy-3,5-dimethoxyphenyl)ethanamine.

Effects

There is limited knowledge regarding the psychopharmacological effects of isoprenaline. In Alexander Shulgin’s PiHKAL, he suggests a psychedelic dosage ranging from 40 to 80 mg, with reported effects lasting approximately 10 to 16 hours.

Pharmacology

The mechanism underlying the hallucinogenic and entheogenic effects of isoprostane is believed to primarily involve its function as a 5-HT2A serotonin receptor agonist in the brain. This mechanism of action is a commonality shared by all hallucinogenic tryptamines and phenethylamines.

Legality

In the United States, Isoproscaline is not classified under any specific schedule. Nonetheless, due to its striking structural and effects resemblance to mescaline, individuals could face legal consequences under the Federal Analog Act for its possession and distribution.
In the United Kingdom, there is a high likelihood that Isoproscaline falls under the “phenylethylamine amendment” to the Misuse of Drugs Act, thereby categorizing it as a Class A controlled substance.

FAQ

1. What is Isoproscaline?

  • Isoproscaline is a chemical compound classified as an analog of mescaline. It is known for its potential psychoactive effects.

2. How is Isoproscaline typically consumed?

  • Isoproscaline is usually taken orally, and the dosage can vary. However, the range provided by Alexander Shulgin in his book PiHKAL is 40 to 80 mg.

3. What are the effects and duration of Isoproscaline use?

  • Isoproscaline is believed to produce hallucinogenic and psychedelic effects. The duration of its effects is estimated to be between 10 to 16 hours.

4. Is Isoproscaline legal in the United States?

  • Isoproscaline is not scheduled in the United States. However, it may still be subject to prosecution under the Federal Analog Act due to its structural and effects similarity to mescaline.

5. What is the legal status of Isoproscaline in the United Kingdom?

  • In the UK, Isoproscaline is likely covered by the “phenylethylamine amendment” to the Misuse of Drugs Act, making it a Class A controlled substance.

6. Are there any known risks associated with Isoproscaline use?

  • Given its limited research and understanding, there may be potential risks associated with Isoproscaline use, including psychological distress and adverse effects. Responsible use and caution are recommended.

7. Can Isoproscaline be used for therapeutic purposes?

  • There is scarce scientific research on the therapeutic potential of Isoproscaline, and it is not approved for medical or therapeutic use. Other psychedelics have been more extensively studied for therapeutic applications.

8. Is Isoproscaline addictive?

  • The addictive potential of Isoproscaline is not well understood. It is generally considered to have a lower risk of physical dependence compared to substances like opioids or stimulants. However, psychological dependence can still occur.

9. Where can I find more information about Isoproscaline?

  • Given the evolving legal and scientific landscape surrounding Isoproscaline, it’s crucial to consult reliable sources of scientific literature and seek advice from healthcare professionals. Staying informed and making well-informed decisions is essential when considering the use of this substance.

References

  1. Isoproscaline entry in PiHKAL

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