4-Acetyloxy-N, N-dipropyltryptamine, or 4-AcO-DPT, belongs to the tryptamine derivative class of compounds. This substance has been marketed and sold as a designer drug. It is essentially an esterified form of 4-HO-DPT, a psychedelic tryptamine initially synthesized by Alexander Shulgin. While anecdotal reports suggest that 4-AcO-DPT induces psychoactive effects in humans, it is worth noting that there has been limited scientific examination of the pharmacological properties of this compound.

CAS Number1445751-75-6
3D model (JSmol)Interactive image
Chemical formulaC18H26N2O2
Molar mass302.418 g·mol−1


  • What is 4-AcO-DPT?4-AcO-DPT, short for 4-Acetyloxy-N,N-dipropyltryptamine, is a chemical compound classified as a tryptamine derivative. It is known for its potential psychoactive effects and has been sold as a designer drug.
  • How is 4-AcO-DPT related to other substances?4-AcO-DPT is an esterified form of 4-HO-DPT, which is a psychedelic tryptamine initially synthesized by Alexander Shulgin. The acetoxy group (AcO) is added to 4-HO-DPT to create 4-AcO-DPT.
  • What are the reported effects of 4-AcO-DPT?Anecdotal reports from users suggest that 4-AcO-DPT can induce various psychoactive effects, including altered perception, visual distortions, and changes in consciousness. However, the specifics of these effects can vary widely among individuals.
  • Is 4-AcO-DPT legal?The legal status of 4-AcO-DPT may vary by country and jurisdiction. In many places, it falls into a legal gray area or is explicitly controlled as a substance. It’s crucial to research and understand the specific regulations in your location before obtaining or using 4-AcO-DPT.
  • How is 4-AcO-DPT typically consumed?4-AcO-DPT can be ingested orally, often in the form of capsules, tablets, or as a powder. Users may choose to measure and consume it in a controlled manner. It’s important to be cautious with dosages and to practice harm reduction principles.
  • What is the pharmacology of 4-AcO-DPT?As of the knowledge cutoff date in September 2021, there has been limited scientific examination of the pharmacological properties of 4-AcO-DPT. Its precise mechanism of action and potential long-term effects are not well understood.
  • Are there any known risks or side effects associated with 4-AcO-DPT?While anecdotal reports suggest its psychoactive effects, there may also be risks associated with using 4-AcO-DPT. Users have reported adverse experiences such as anxiety, nausea, and confusion. Like with other psychedelics, set (mindset) and setting (environment) play a significant role in the user’s experience.
  • Is 4-AcO-DPT addictive?As of the knowledge cutoff date in September 2021, there is no strong evidence to suggest that 4-AcO-DPT is physically addictive. However, there could be a potential for psychological dependence, where users develop a habit of using it excessively.
  • Is 4-AcO-DPT used for therapeutic purposes?4-AcO-DPT has not been extensively studied for therapeutic applications. Research into its potential therapeutic effects, if any, is limited. It should only be used for therapeutic purposes under the guidance of a qualified healthcare professional.
  • Where can I obtain 4-AcO-DPT?The availability of 4-AcO-DPT can vary, and its sale may be subject to legal restrictions. Obtaining it from unverified sources can be risky, as the purity and quality of the substance may not be guaranteed. It’s important to exercise caution and, ideally, seek reputable sources if considering acquiring it.


  1. Schifano, Fabrizio; Orsolini, Laura; Papanti, Duccio; Corkery, John (2017). “Neuropharmacology of new psychoactive substances (NPS): the science behind the headlines.” Current Topics in Behavioral Neurosciences. Vol. 32. Cham, Switzerland: Springer. Pages 351–380. doi:10.1007/978-3-319-52444-3. ISBN 978-3-319-52444-3. S2CID 23812562. Retrieved 14 January 2021.
  2. Nervewing. “Greater Mind Lesser Body.” Erowid Experience Vaults. Erowid. Retrieved 14 January 2021.
  3. “Tihkal 4-HO-DIPT entry.”

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