Summary
3,4-Dimethylmethcathinone (3,4-DMMC), often referred to as 3,4-DMMC, is a stimulant substance initially documented in 2010 as a designer drug analog of mephedrone. This emergence appeared in response to the prohibition of mephedrone due to its widespread misuse in various countries across Europe and worldwide. Notably, 3,4-DMMC has been confiscated as a designer drug in Australia.
In laboratory studies, 3,4-DMMC has demonstrated properties as a substrate for monoamine transporters, exerting potent inhibitory effects on the reuptake of norepinephrine and serotonin, with a comparatively lesser impact on dopamine reuptake.
| Identifiers | |
|---|---|
| IUPAC name | |
| CAS Number | 1082110-00-6 |
|---|---|
| PubChem CID | 52988261 |
| ChemSpider | 25630192 |
| UNII | C4EW58DTW5 |
| Chemical and physical data | |
| Formula | C12H17NO |
| Molar mass | 191.274 g·mol−1 |
Legal Status
- China classified 3,4-DMMC as a controlled substance as of October 2015.
- The Czech Republic has prohibited the use of 3,4-DMMC.
- In the United States, 3,4-DMMC is categorized as a Schedule 1 controlled substance due to its status as a positional isomer of 4-Methylethcathinone (4-MEC).
FAQ
1. What is 3,4-Dimethylmethcathinone (3,4-DMMC)?
- 3,4-DMMC is a synthetic stimulant drug that belongs to the cathinone class. It is structurally related to mephedrone and stimulates the central nervous system.
2. When was 3,4-DMMC first reported?
- 3,4-DMMC was first reported in 2010 as a designer drug analog of mephedrone. It appeared to emerge in response to banning of mephedrone in several countries.
3. Is 3,4-DMMC legal?
- The legal status of 3,4-DMMC varies from country to country. As of my last knowledge update in September 2021, it was classified as a controlled substance in some regions, including China and the United States, while it was banned in others, like the Czech Republic. It’s crucial to check local laws and regulations for current information.
4. What are the effects of 3,4-DMMC?
- 3,4-DMMC is known to have stimulant properties, similar to other cathinone derivatives. Users may experience increased alertness, energy, and euphoria. However, these effects can vary from person to person, and the compound’s safety profile needs to be better understood.
5. Are there any health risks associated with 3,4-DMMC use?
- The health risks associated with 3,4-DMMC use are not well-documented due to limited scientific research. Like other stimulants, it may carry risks such as increased heart rate, blood pressure, and potential for addiction. It’s essential to exercise caution and avoid its use without proper guidance.
6. Is 3,4-DMMC used for any medical purposes?
- As of my last update in September 2021, 3,4-DMMC had no recognized medical applications and was primarily encountered as a recreational or designer drug.
The legal and scientific landscape surrounding 3,4-DMMC may have evolved since my last update in September 2021. Stay informed about this compound’s latest developments and regulations if you have any concerns or interests in its use or research.
References
- The “EMCDDA Annual Report 2010” was published as a PDF document and is available in the archives. It can be accessed through the original PDF link, which was last checked on March 14, 2012, and retrieved on October 3, 2011.
- In September 2012, Locos O and Reynolds D conducted a study titled “The characterization of 3,4-dimethylmethcathinone (3,4-DMMC).” This research was published in the Journal of Forensic Sciences (Volume 57, Issue 5), and it can be referenced with the DOI: 10.1111/j.1556-4029.2012.02142.x. The PMID is 22564211, and the S2CID is 205770717.
- In 2018, Luethi D, Kolaczynska KE, Docci L, Krähenbühl S, Hoener MC, and Liechti ME conducted a study on the pharmacological profile of mephedrone analogs and related new psychoactive substances. The research was published in Neuropharmacology (Volume 134) and is available as a PDF. It can be referenced with the DOI: 10.1016/j.neuropharm.2017.07.026. The PMID is 28755886, and the S2CID is 28786127.
- The China Food and Drug Administration issued a notice in Chinese titled “关于印发《非药用类麻醉药品和精神药品列管办法》的通知” on September 27, 2015. This notice is related to the management of non-medical narcotics and psychotropic substances.
- The Czech Ministry of Health supplemented the list of psychotropic substances with a document titled “Látky, o které byl doplněn seznam č. 4 psychotropních látek (příloha č. 4 k nařízení vlády č. 463/2013 Sb.)” in PDF format. This supplementation was done as an appendix to government regulation number 463/2013 Sb.
- The U.S. Department of Justice published a document titled “Lists of: Scheduling Actions Controlled Substances Regulated Chemicals” in February 2023. This document contains information regarding scheduling actions, controlled substances, and regulated chemicals. It was last retrieved on March 5, 2023.