Summary 3-Chloro-PCP, also known as 3′-Cl-PCP, is a synthetic designer drug classified within the arylcyclohexylamine family. It is renowned for its dissociative effects. While it exhibits potency similar to phencyclidine (PCP), it offers a slightly distinct effects profile. Specifically, it is recognized for its enhanced potency as an NMDA antagonist while maintaining a comparable strength …
Summary Trifluoromethyldeschloroketamine, known as TFMDCK, is a member of the arylcyclohexylamine designer drug category. It is believed to share specific properties with ketamine, a dissociative anesthetic renowned for its hallucinogenic and sedative effects. TFMDCK has been available for purchase on the internet since approximately 2016, although authentic samples seem to be scarce. Additionally, the o-trifluoromethyl …
Summary Deoxymethoxetamine, also known as 3′-methyl-2-oxo-PCE, DMXE, or 3D-MXE, is a synthetic designer drug classified within the arylcyclohexylamine family, known for its dissociative effects. This substance is a derivative of methoxetamine, with the 3-methoxy group being substituted by a methyl group. It became available for online purchase approximately in October 2020, and a forensic laboratory …
Summary 2-Oxo-PCE, which is also referred to as N-ethyldeschloroketamine, eticyclidone, and O-PCE, is a dissociative anesthetic belonging to the arylcyclohexylamine class. It shares a close structural resemblance with deschloroketamine and eticyclidine and has been available for purchase online as a designer drug. Identifiers IUPAC name CAS Number 6740-82-5 hydrochloride: 4551-92-2 PubChem CID 132989542 ChemSpider 76590394 UNII 2TRF16U3MRhydrochloride: 6Q4N3KH3MG …
Summary 3-Fluorodeschloroketamine (often abbreviated as 3F-DCK, 3-FDCK, or FXM) belongs to the family of arylcyclohexylamine designer drugs and is associated with recreational use similar to ketamine. This substance produces dissociative effects. Finland officially prohibited its possession and use in August 2019. Identifiers IUPAC name CAS Number 2657761-23-2 PubChem CID 156538475 Chemical and physical data Formula …
Summary 2-Fluorodeschloroketamine (also identified as 2′-Fl-2-Oxo-PCM, Fluoroketamine, and 2-FDCK) is a dissociative anesthetic compound closely related to ketamine. There have been reports of its sale and use as a designer drug in various countries. This substance is an analog of ketamine, with the chlorine group replaced by fluorine. Given its recent emergence, many pharmacological details regarding …
Summary 2-Bromodeschloroketamine (also referred to as 2-Br-2′-Oxo-PCM and Bromoketamine) is a chemical compound categorized within the arylcyclohexylamine class. It is analogous to the dissociative anesthetic drug ketamine, wherein the chlorine atom is substituted with a bromine atom. This compound is primarily utilized in scientific research as a reference or control substance in investigations focused on the …
Summary Methylhexanamine, also known as methylhexanamine, 1,3-dimethylamylamine, 1,3-DMAA, dimethylamylamine, and DMAA, was created and developed by Eli Lilly and Company. It was introduced as an inhaled nasal decongestant in 1948 and remained on the market until the 1980s when it was voluntarily withdrawn.Since 2006, methylhexanamine has resurfaced under various names and has been widely sold …
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Summary Mazindol, available under brand names such as Mazanor and Sanorex, is classified as a stimulant medication primarily employed for appetite suppression. This medication was originally formulated by Sandoz-Wander during the 1960s. Identifiers IUPAC name CAS Number 22232-71-9 PubChem CID 4020 IUPHAR/BPS 4797 DrugBank DB00579 ChemSpider 3880 UNII C56709M5NH KEGG D00367 ChEMBL ChEMBL781 CompTox Dashboard …
Summary Diclofensine (Ro 8-4650) emerged from Hoffmann-La Roche’s research efforts in the 1970s aimed at discovering a novel antidepressant. Subsequent investigations revealed that the active component was the (S)-isomer. This compound functions as a stimulant by operating as a triple monoamine reuptake inhibitor, primarily impeding the reuptake of dopamine and norepinephrine, exhibiting binding affinities (Ki) …
