Summary MMDA-2, formally known as 2-methoxy-4,5-methylenedioxyamphetamine, is a member of the psychedelic amphetamine class. It shares a close chemical kinship with substances like MMDA and MDA.The pioneering synthesis of MMDA-2 is often attributed to Alexander Shulgin, a prominent figure in the realm of psychopharmacology. In his comprehensive book “PiHKAL,” Shulgin notes that the recommended dosage …
Summary 3,4-Methylenedioxy-N-hydroxy-N-methylamphetamine (MDHMA), also known as FLEA, falls within the realm of entactogenic, psychedelic, and stimulant compounds, classifying it under the phenethylamine and amphetamine chemical categories. This chemical entity serves as the N-hydroxy homolog of MDMA, commonly referred to as “Ecstasy,” and the N-methyl homolog of MDOH. Alexander Shulgin carried out the pioneering work on …
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Summary 3,4-Ethylenedioxy-N-methylamphetamine (EDMA) is a member of the entactogen drug family belonging to the methamphetamine class. In essence, it is an analog of MDMA, where the characteristic methylenedioxy ring has been replaced by an ethylenedioxy call. The synthesis of EDMA is credited to Alexander Shulgin. In his notable work “PiHKAL,” the recommended dosage for EDMA …
Summary N,N-Dimethylpentylone, commonly referred to as Dipentylone or simply Dimethylpentylone, is a derivative of cathinone with stimulant properties. This compound has been marketed as a designer drug and was initially identified in Sweden in 2014. Identifiers IUPAC name CAS Number 803614-36-0 17763-13-2 (Hydrochloride) PubChem CID 119057570 ChemSpider 52085278 UNII V41961I345 Chemical and physical data Formula C14H19NO3 …
Summary Difluoromethylenedioxyamphetamine (DiFMDA) is a modified derivative of 3,4-methylenedioxyamphetamine (MDA), a compound initially developed by Daniel Trachsel and colleagues. This development also included the creation of fluorinated variants of MDMA, MDEA, BDB, and MBDB. The primary objective was to identify a non-neurotoxic substance that could serve as a safer alternative to entactogenic drugs like MDMA.The …
Summary Trimethoxyamphetamines (TMAs) comprise a group of isomeric psychedelic hallucinogenic substances. There are six distinct TMAs, differentiated solely by the arrangement of three methoxy groups: TMA, TMA-2, TMA-3, TMA-4, TMA-5, and TMA-6. These compounds are analogs of mescaline, a phenethylamine cactus alkaloid. TMAs are substituted amphetamines, and their action mechanism is more intricate than the unaltered …
Summary N,α-Diethylphenethylamine (N,α-DEPEA), also known as 2-ethylamino-1-phenylbutane (EAPB), is a chemical compound closely related to methamphetamine and has gained attention as a designer drug. Initially, it was patented by Knoll Pharma as part of a series of analogs intended for potential pharmaceutical applications. Preclinical studies involving these analogs in animal models indicated cognitive enhancement and …
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Summary β-Phenylmethamphetamine, also known as N,α-dimethyl-β-phenyl-phenethylamine, is a highly potent and enduring stimulant substance. Identifiers IUPAC name CAS Number 768295-94-93139-56-8 (hydrochloride) PubChem CID 201042 ChemSpider 174060 UNII 13B0I1EGF7 CompTox Dashboard (EPA) DTXSID70276795 Chemical and physical data Formula C16H19N Molar mass 225.335 g·mol−1 FAQ 1. What is Beta-Phenylmethamphetamine (BPM)? 2. Is BPM the same as Methamphetamine or …
Summary 3-Methylamphetamine (3-MeA; PAL-314) is classified as a stimulant compound belonging to the amphetamine family. When tested in mice, it exhibits a self-administration behavior similar to that observed with 4-fluoroamphetamine. Notably, it shares characteristics with monoamine releasers, although it distinguishes itself by facilitating a more evenly distributed release of all three monoamines. This sets it …
Summary Ortetamine (INN), recognized as 2-methylamphetamine, belongs to the amphetamine class of stimulant drugs. In animal tests for drug discrimination, it demonstrated a closer similarity to dextroamphetamine compared to 3- or 4-methylamphetamine, albeit with approximately one-tenth the potency of dextroamphetamine. Identifiers IUPAC name CAS Number 5580-32-5 PubChem CID 115808 ChemSpider 103572 UNII VF4N11KKKR CompTox Dashboard …
