1-(3,4-Methylenedioxybenzyl)piperazine, also known as MDBZP or piperonylpiperazine, is a chemical compound within the piperazine class, bearing a close relation to benzylpiperazine (BZP). MDBZP has been distributed as a designer drug and has been detected as an additive in street Ecstasy tablets.

IUPAC name
CAS Number32231-06-4 
PubChem CID94426
CompTox Dashboard (EPA)DTXSID70185994
ECHA InfoCard100.046.319
Chemical and physical data
Molar mass220.272 g·mol−1


  1. What is Methylenedioxybenzylpiperazine (MDBZP)?
    • Methylenedioxybenzylpiperazine, commonly abbreviated as MDBZP, is a chemical compound belonging to the piperazine class. It shares chemical similarities with benzylpiperazine (BZP).
  2. What are the characteristics of MDBZP?
    • MDBZP is known for its chemical structure, which includes a methylenedioxybenzyl group attached to a piperazine ring. This structural similarity to other compounds can affect its potential effects and legal status.
  3. Has MDBZP been used as a recreational drug?
    • Yes, MDBZP has been sold and consumed as a designer drug, often with psychoactive effects. It has also been detected as an ingredient in street Ecstasy pills.
  4. Is MDBZP legal?
    • The legal status of MDBZP can vary by country and region. It may be categorized as a controlled substance in some areas, while in others, it might not have specific legal restrictions.
  5. What effects are associated with MDBZP use?
    • The effects of MDBZP can vary, but it is generally considered to have psychoactive properties. These effects can include changes in mood, perception, and sensory experiences.
  6. Are there potential risks or side effects associated with MDBZP use?
    • As with many designer drugs, there can be health risks and side effects associated with the use of MDBZP. These may include nausea, anxiety, and other adverse reactions, and the safety of its use is not well-documented.
  7. Is MDBZP related to other substances or compounds?
    • MDBZP is chemically related to benzylpiperazine (BZP) due to its piperazine structure. It’s important to note that these relationships can affect how a substance is regulated legally and its potential effects.
  8. Is there any medical use for MDBZP?
    • MDBZP is not approved for any medical use and is primarily encountered in recreational or illicit contexts.
  9. Is the legal status of MDBZP subject to change?
    • The legal status of MDBZP can change over time as new legislation and regulations are introduced. It is crucial to stay informed about the laws in your specific location if you have concerns about its use or possession.
  10. Is MDBZP regulated by international drug control agreements?
  • The classification and regulation of MDBZP can vary from country to country, and it may not always be explicitly addressed by international drug control agreements. Compliance with national laws and regulations is essential.


  1. Maurer HH, Kraemer T, Springer D, Staack RF (April 2004). “Chemistry, pharmacology, toxicology, and hepatic metabolism of designer drugs of the amphetamine (ecstasy), piperazine, and pyrrolidinophenone types: a synopsis”. Therapeutic Drug Monitoring. 26 (2): 127–31. doi:10.1097/00007691-200404000-00007. PMID15228152. S2CID9255084.

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