Summary RCS-4, also known as 1-pentyl-3-(4-methoxybenzoyl)indole, is a synthetic cannabinoid compound that has been marketed and sold under various names, including SR-19, BTM-4, Eric-4 (later abbreviated to E-4), and initially, OBT-199. Identifiers IUPAC name CAS Number 1345966-78-0 ChemSpider 24769418 UNII Y6911BZ2UL CompTox Dashboard (EPA) DTXSID70158820 ECHA InfoCard 100.233.383 Chemical and physical data Formula C21H23NO2 Molar …
Summary AM-2233 is a pharmaceutical compound recognized for its exceptional role as a potent full agonist for cannabinoid receptors. Specifically, the (R) enantiomer of AM-2233 exhibits a remarkable Ki of 1.8 nM at CB1 and 2.2 nM at CB2, underscoring its potent activity at these receptors.One of its primary purposes is as a selective radioligand …
Summary AM-1241, also known as 1-(methylpiperidin-2-ylmethyl)-3-(2-iodo-5-nitrobenzoyl)indole, is a member of the aminoalkylindole family, recognized for its role as a potent and highly selective agonist for the cannabinoid receptor CB2. With a remarkable Ki value of 3.4 nM at CB2, it exhibits substantial selectivity, being approximately 80 times more selective for CB2 compared to the related …
Summary AM-694, known chemically as 1-(5-fluorophenyl)-3-(2-iodobenzoyl)indole, functions as a designer drug with a specific role as a potent and selective agonist for the cannabinoid receptor CB1. This compound is frequently utilized in scientific research to map the distribution of CB1 receptors within the body. Identifiers IUPAC name CAS Number 335161-03-0 PubChem CID 9889172 ChemSpider 8064843 …
Summary AM-679, a member of the AM cannabinoid series, is a moderately potent agonist for cannabinoid receptors. It exhibits a Ki of 13.5 nM at CB1 and 49.5 nM at CB2, signifying its affinity for these receptors. Notably, AM-679 was among the pioneering 3-(2-iodobenzoyl)indole derivatives to display a noteworthy affinity for cannabinoid receptors. While AM-679 …
Summary AM-630, or 6-Iodopravadoline, is a potent and highly selective inverse agonist targeting the cannabinoid receptor CB2. It exhibits a remarkable affinity for CB2, boasting a Ki value of 32.1 nM, while showing a notable 165-fold selectivity over CB1 receptors, where it only exhibits weak partial agonist activity. Researchers employ AM-630 to investigate CB2-mediated responses, …
