Summary Benzylbutylbarbiturate, scientifically referred to as 5-benzyl-5-n-butylbarbituric acid, stands as an uncommon instance of a designer drug within the barbiturate class, potentially one of the few of its kind identified in recent times. This substance came to the attention of law enforcement in Japan in the year 2000, and it is presumed to have been …
Summary 4-Fluorophenibut, which also goes by the developmental code name CGP-11130, is recognized as β-(4-fluorophenyl)-γ-aminobutyric acid or β-(4-fluorophenyl)-GABA. It operates as an agonist for the GABAB receptor, although it never reached the commercial market.In its selectivity, 4-Fluorophenibut demonstrates a preference for the GABAB receptor over the GABAA receptor, with respective IC50 values of 1.70 μM …
Summary 2-Methyl-2-pentanol, also known by its IUPAC name, 2-methylpentan-2-ol, is an organic chemical compound. It finds utility in gas chromatography as an additive for the differentiation of branched compounds, particularly alcohols, due to its unique properties.Moreover, the detection of 2-Methyl-2-pentanol in urine serves as an indicator for exposure to 2-methylpentane, making it valuable in toxicological …
Summary Throughout its history, Trichloroethanol (TAA) has served as an anesthetic, as documented in the past. More recently, it has gained notoriety as a recreational drug. TAA primarily functions as a positive allosteric modulator for GABAA receptors, akin to ethanol. Notably, both TAA and ethanol share psychotropic effects, although each possesses distinct characteristics. TAA tends …
Summary SL-164, also recognized as dicloqualone or DCQ, is a compound that serves as an analogue of methaqualone. It was formulated in the late 1960s by a research team at Sumitomo. SL-164 shares comparable properties, including sedative, hypnotic, and anticonvulsant effects, with its parent compound. However, it was never introduced to the clinical market for …
Summary Nitromethaqualone, often referred to as NMQ, is a chemical analog of methaqualone known for sharing similar sedative and hypnotic properties. Notably, Nitromethaqualone exhibits significantly increased potency, being approximately ten times more potent than its parent compound. A typical dosage of Nitromethaqualone is around 25 milligrams. Identifiers IUPAC name CAS Number 340-52-3 PubChem CID 63339 …
Sumamry Methylmethaqualone (MMQ) is a compound classified under the quinazolinone group and serves as an analog of methaqualone. It shares similar sedative and hypnotic properties with its parent compound, primarily due to its agonistic influence on the β subtype of the GABAA receptor. Notably, in animal models, Methylmethaqualone has been shown to be approximately three …
Summary Mecloqualone, also known by trade names such as Nubarene and Casfen, belongs to the Quinazolinone class of compounds. It is categorized as a GABAergic substance and serves as an analog of methaqualone. This compound was first synthesized in 1960 and primarily found its market in France and several other European countries. Mecloqualone exhibits notable …
Summary Mebroqualone (often abbreviated as MBQ) belongs to the quinazolinone class of compounds and is recognized as a GABAergic substance. It serves as an analog of mecloqualone, sharing comparable sedative and hypnotic properties with its parent compound, owing to its agonistic effects at the β subtype of the GABA receptor. The synthesis of Mebroqualone dates …
Summary Methaqualone, known by trade names such as Aolan, Athinazone, and Ethinazone, belongs to the quinazolinone class of compounds. This substance is a GABAergic agent and serves as an analog of methaqualone. It was initially developed during the 1960s and found its primary market in France and a few other European countries. Ethaqualone exhibits various …
