Summary MEPIRAPIM, classified as an indole-based cannabinoid, distinguishes itself from JWH-018 by featuring a 4-methylpiperazine group instead of the naphthyl group. This compound has found applications as a critical component in synthetic cannabis products. Its discovery dates back to 2013, when it was initially recognized in Japan alongside FUBIMINA. It’s worth noting that MEPIRAPIM primarily …
Summary MDMB-FUBICA, an indole-based synthetic cannabinoid, is thought to exhibit strong agonistic activity on the CB1 receptor and has gained notoriety as a designer drug available for online purchase. The EMCDDA first identified MDMB-FUBICA in Sweden in February 2015. This synthetic compound is commonly marketed in e-liquid form, intended for use in electronic cigarettes. Identifiers …
Summary MDMB-CHMICA, classified as an indole-based synthetic cannabinoid, exhibits robust agonistic activity toward the CB1 receptor and has been commercialized online as a designer drug. Notably, while it was initially available under the name “MMB-CHMINACA,” the version corresponding to this codename (distinguished by the presence of isopropyl instead of t-butyl) emerged as AMB-CHMINACA in the …
Summary FUB-144, alternatively known as FUB-UR-144, belongs to the family of synthetic cannabinoids with an indole base. This compound is believed to exhibit vigorous agonistic activity toward the CB1 receptor and has been distributed on the internet as a designer drug. It is an analogue of UR-144 and XLR-11, differing in that the pentyl chain …
Summary FDU-NNE1, alternatively known as FDU-NNEI and FDU-MN-24, is a synthetic cannabinoid with an indole-based structure. It is believed to act as a potent agonist of the CB1 receptor and has been available for purchase as a designer drug through online channels. An interesting note is that similar to its related compound APINACA, the metabolic …
Summary CUMYL-PICA, or SGT-56, is a synthetic cannabinoid rooted in indole-3-carboxamide. This compound represents the α,α-dimethylbenzyl analogue of SDB-006. Notably, it made a brief appearance in the New Zealand market in 2013 as an ingredient in synthetic cannabis products, which were legal at the time. However, the product containing CUMYL-BICA and CUMYL-PICA faced a setback …
Summary CUMYL-PEGACLONE, also known as SGT-151, is a synthetic cannabinoid rooted in the gamma-carboline structure and has been available as a designer drug. What sets CUMYL-PEGACLONE apart is its unique gamma-carboline core structure, which had not been observed in designer cannabinoids previously. However, it resembles other gamma-carboline cannabinoids disclosed by Bristol-Myers Squibb in 2001. Identifiers …
Summary BzODZ-EPyr is a synthetic cannabinoid with an indole base and has been marketed as a designer drug in Russia.This compound functions as a CB1 receptor agonist, boasting a pKB value 7.2. Notably, it highlights that substituting the ketone in 3-carbonyl indoles with an oxadiazole spacer typically does not result in a loss of activity. …
Summary MMB-CHMICA, also known as AMB-CHMICA, is a synthetic cannabinoid and designer drug. In the year 2018, it held the distinction of being the sixth most frequently encountered synthetic cannabinoid in substances confiscated by the Drug Enforcement Administration. Identifiers IUPAC name CAS Number 1971007-94-9 ChemSpider 68896113 UNII HEN6ZCR7GD CompTox Dashboard (EPA) DTXSID301009991 Chemical and physical …
Summary APICA also referred to as 2NE1, SDB-001, or N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide, stands as an indole-based compound renowned for its robust agonistic effects on cannabinoid receptors.This distinctive compound debuted in the scientific and patent literature when laboratories in Japan identified it in March 2012. It was found as an ingredient in synthetic cannabis smoking blends, notably in …
