Summary U-47700 also recognized as U4, pink heroin, pinky, or pink, is an opioid analgesic drug initially developed by a team at Upjohn during the 1970s. In animal models, it boasts approximately 7.5 times the potency of morphine.A physical sample of U-47700 is available for reference.This compound is a structural isomer of the earlier opioid …
Summary Methylhexanamine, also known as methylhexanamine, 1,3-dimethylamylamine, 1,3-DMAA, dimethylamylamine, and DMAA, was created and developed by Eli Lilly and Company. It was introduced as an inhaled nasal decongestant in 1948 and remained on the market until the 1980s when it was voluntarily withdrawn.Since 2006, methylhexanamine has resurfaced under various names and has been widely sold …
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Summary Mazindol, available under brand names such as Mazanor and Sanorex, is classified as a stimulant medication primarily employed for appetite suppression. This medication was originally formulated by Sandoz-Wander during the 1960s. Identifiers IUPAC name CAS Number 22232-71-9 PubChem CID 4020 IUPHAR/BPS 4797 DrugBank DB00579 ChemSpider 3880 UNII C56709M5NH KEGG D00367 ChEMBL ChEMBL781 CompTox Dashboard …
Summary Diclofensine (Ro 8-4650) emerged from Hoffmann-La Roche’s research efforts in the 1970s aimed at discovering a novel antidepressant. Subsequent investigations revealed that the active component was the (S)-isomer. This compound functions as a stimulant by operating as a triple monoamine reuptake inhibitor, primarily impeding the reuptake of dopamine and norepinephrine, exhibiting binding affinities (Ki) …
Summary Bromantane, marketed under the brand name Ladasten, is an unconventional psychostimulant and anxiolytic medication belonging to the adamantane family, sharing connections with amantadine and memantine. It finds usage in Russia for the treatment of neurasthenia. Although researchers have established that bromantane’s effects are tied to the dopaminergic and potentially serotonergic neurotransmitter systems, the precise …
Summary Amfonelic acid (AFA), also known as WIN 25,978, is a research compound and dopaminergic stimulant that possesses antibiotic characteristics. While there is a scarcity of extensive clinical trials involving AFA, it is predominantly employed within the realm of scientific research. Identifiers IUPAC name CAS Number 15180-02-6 PubChem CID 2137 ChemSpider 2052 UNII RR302AR19Y KEGG …
Summary 2-Aminoindane (2-AI) is a compound utilized in scientific research for its potential in addressing neurological conditions and supporting psychotherapy practices. Additionally, it has found its way into the market as a designer drug. Its primary mechanism of action involves its selective interaction with the norepinephrine transporter (NET) and dopamine transporter (DAT). Identifiers IUPAC name …
Summary Viloxazine, available under the brand name Qelbree and formerly known as Vivalan and by other trade names, is a medication classified as a selective norepinephrine reuptake inhibitor (NRI). It is employed in the treatment of attention deficit hyperactivity disorder (ADHD) in both children and adults. Interestingly, Viloxazine had a prior history of almost three …
Summary 3-Fluorophenmetrazine, commonly referred to as 3-FPM and also known as 3-FPH and PAL-593, is a stimulant with its foundation in phenylmorpholine. This chemical compound serves as a fluorinated derivative of phenmetrazine and has been distributed via online sources under the guise of a designer drug. Identifiers IUPAC name CAS Number 1350768-28-3 HCl: 1803562-83-5 PubChem CID 54673723HCl: …
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Summary 4,4′-Dimethylaminorex, commonly referred to as 4,4′-DMAR and colloquially known as “Serotonin,” belongs to the category of psychostimulant and entactogen designer drugs. This compound shares chemical similarities with aminorex, 4-methylaminorex, and pemoline. It was initially identified in the Netherlands in December 2012 and subsequently emerged in the European designer drug market around mid-2013.By February 2014, …
