Summary Aleph, also recognized as DOT or 2,5-dimethoxy-4-methylthioamphetamine, belongs to the class of substituted amphetamines within the phenethylamine compound group, renowned for its hallucinogenic properties. This compound can serve as a psychedelic drug and is often employed as an entheogen. The distinguished chemist Alexander Shulgin pioneered its synthesis and bestowed the name “Aleph” in homage …
Summary Identifiers IUPAC name CAS Number 1354632-01-1 PubChem CID 57501069 ChemSpider 25949200 UNII NS6YSG7F4H Chemical and physical data Formula C19H25NO4 Molar mass 331.412 g·mol−1 NBOMe-mescaline or mescaline-NBOMe is a synthetic substituted phenethylamine that acts as a partial agonist of serotonin receptors. It has a 5-HT2A pKi of 7.3 (i.e., Ki of approximately 50nM) as initially reported. …
Summary 25P-NBOMe, also known as 2C-P-NBOMe or NBOMe-2C-P, belongs to the phenethylamine family and is derived from 2C-P. Its pharmacological behaviour closely resembles other compounds, notably 25I-NBOMe, which exhibits potent agonistic activity at the 5HT2A receptor. The substance has been distributed in the market as a recreational drug. It is known to elicit effects in …
Summary 25N-NBOMe (2C-N-NBOMe, NBOMe-2C-N) represents a derivative of the hallucinogenic compound 2C-N. Although the scientific literature has not extensively explored the pharmacological properties 25N-NBOMe, it is believed to operate similarly to its related counterparts, such as 25I-NBOMe and 25C-NBOMe. These related compounds are recognized as potent agonists at the 5HT2A receptor. Notably, 25N-NBOMe has been …
Summary 25H-NBOMe (also known as NBOMe-2C-H) is a compound derived from the phenethylamine hallucinogen 2C-H. It functions as a remarkably potent full agonist targeting the human 5-HT2A receptor. Identifiers IUPAC name CAS Number 919797-16-3 PubChem CID 39424372 ChemSpider 25511924 UNII RN5ZVN74Y9 Chemical and physical data Formula C18H23NO3 Molar mass 301.386 g·mol−1 Toxicity NBOMe substances are frequently …
Summary 25iP-NBOMe (2C-iP-NBOMe, NBOMe-2C-iP) is a compound derived from the phenethylamine hallucinogen 2C-iP, renowned for its exceptional potency as an agonist for the human 5-HT2A receptor. Identifiers IUPAC name CAS Number 1391487-83-4 PubChem CID 118796426 ChemSpider 52085379 UNII 575702U55U Chemical and physical data Formula C21H29NO3 Molar mass 343.467 g·mol−1 Toxicity and harm potential NBOMe compounds are …
Summary 25I-NBOH (also known as NBOH-2CI, Cimbi-27, 2-C-I-NBOH) belongs to the group of derivatives derived from the phenethylamine hallucinogen 2C-I, initially discovered in 2006 by a team at Purdue University. Identifiers IUPAC name CAS Number 919797-20-9 PubChem CID 10001761 ChemSpider 8177342 UNII W9G4BGW8K4 CompTox Dashboard (EPA) DTXSID80433993 Chemical and physical data Formula C17H20INO3 Molar mass …
Summary 25I-NBMD (NBMD-2C-I, Cimbi-29) was first identified as a derivative of the phenethylamine hallucinogen 2C-I in 2006 by Purdue University researchers under David Nichols’s leadership. Acting as a potent partial agonist for the 5HT2A receptor, it exhibits a Ki of 0.049 nM at the human 5HT2A receptor. Notably, the related 4-bromo analogue, 25B-NBMD, has been …
Summary 25I-NBF (2C-I-NBF, NBF-2C-I, Cimbi-21) is a compound derived from the phenethylamine hallucinogen 2C-I. It exhibits potent partial agonism for the human 5-HT2A receptor, known for its involvement in various neurological processes. Notably, it isn’t very objective towards the β-arrestin 2 coupled signalling pathway, indicating its complex interaction within the receptor system. In research, its …
Summary 25E-NBOMe (also known as 2C-E-NBOMe or NBOMe-2C-E) is a chemical derivative originating from the phenethylamine 2C-E. It exhibits analogous behaviour to its counterparts, including 25I-NBOMe, known for their powerful activation of the 5HT2A receptor. This substance has been circulated as a recreational drug, eliciting effects comparable to related compounds like 25I-NBOMe and 25C-NBOMe in …
