Summary JWH-133, also known as Dimethylbutyl-deoxy-Delta-8-THC, stands out as a potent and highly selective agonist of the CB2 receptor, exhibiting a remarkable Ki value of 3.4nM and an impressive selectivity of approximately 200 times for CB2 over CB1 receptors. This compound owes its name to the pioneering researcher John W. Huffman.In scientific literature, JWH-133 has …
Summary JWH-051 is an analgesic medication that functions as a cannabinoid agonist. Its chemical structure closely resembles the potent cannabinoid agonist HU-210, with the sole distinction being the absence of the hydroxyl group at position 1 of the aromatic ring. This compound was first identified and named in honor of John W. Huffman.JWH-051 maintains a …
Summary HU-210, a synthetic cannabinoid, was initially synthesized in 1988 by a research team led by Raphael Mechoulam at the Hebrew University. It boasts an astonishing potency, ranging from 100 to 800 times greater than naturally occurring THC found in cannabis. Additionally, HU-210 exhibits a significantly prolonged duration of action. In terms of its receptor …
Summary Dimethylheptylpyran, also known as DMHP, 3-(1,2-dimethylheptyl)-Δ6a(10a)-THC, 1,2-dimethylheptyl-Δ3-THC, A-40824, or EA-2233, represents a synthetic analogue of THC. This compound was first developed in 1949 as part of scientific efforts aimed at unraveling the structure of Δ9-THC, one of the primary active constituents found in Cannabis. DMHP presents itself as a pale yellow, viscous oil that …
Summary Parahexyl, also known as Synhexyl or n-hexyl-Δ3-THC, is a synthetic counterpart to THC (tetrahydrocannabinol). It was developed in 1941 as part of efforts to decipher the chemical structure of Δ9-THC, one of the primary active compounds found in cannabis.Parahexyl closely resembles THC in terms of both its structure and its effects, with the only …
Summary Nabilone, marketed under the trade name Cesamet and other brands, is a synthetic cannabinoid recognized for its therapeutic applications as an antiemetic and as a supplementary analgesic in managing neuropathic pain. This compound emulates tetrahydrocannabinol (THC), the primary psychoactive component naturally found in the Cannabis plant. In the United States, the Food and Drug …
Summary Clonidine, marketed under various trade names such as Catapres, Kapvay, Nexiclon, Clophelin, and more, is categorized as a depressant belonging to the imidazoline class of substances. While its primary application is in managing high blood pressure, it is versatile and can be employed for various medical conditions. These include attention deficit hyperactivity disorder, anxiety …
The market situation for MDA (3,4-methylenedioxyamphetamine) is undergoing significant changes, primarily influenced by shifting regulations and consumer preferences. MDA, once a prominent designer drug and research chemical, is now subject to increased scrutiny and restrictions.For sellers and vendors, the landscape has become increasingly challenging. Many online platforms have yet to crack down on the sale …
Online vendors have become a prominent source for individuals looking to buy 5-HTP supplements. These products are readily available for sale on various e-commerce platforms and websites specializing in dietary supplements. Sellers often market 5-HTP as a dietary supplement rather than a designer drug or research chemical, emphasizing its natural origins and potential health benefits.However, …
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When purchasing research chemicals online, the market is flooded with sellers offering various substances, including the controversial 5F-AKB48. While there may be legitimate reasons for researchers to seek out such compounds, the online marketplace for these substances is fraught with risks and ethical concerns.One of the primary issues surrounding 5F-AKB48 research chemical sellers is the …
