Summary Trimethoxyamphetamines (TMAs) constitute a family of isomeric psychedelic hallucinogenic substances. This family comprises six distinct TMAs, each differing solely in the arrangement of three methoxy groups: TMA, TMA-2, TMA-3, TMA-4, TMA-5, and TMA-6. These TMAs are analogs of the phenethylamine cactus alkaloid mescaline. While they fall under the category of substituted amphetamines, their mechanism …
Summary 2,5-Dimethoxy-4-propylamphetamine (DOPR) belongs to the phenethylamine and amphetamine chemical classes and was initially synthesized by Alexander Shulgin. Shulgin introduced this compound in his renowned work, “PiHKAL” (Phenethylamines I Have Known And Loved). DOPR, according to Shulgin, is a profoundly potent psychedelic substance capable of inducing substantial alterations in thought processes and significant visual distortions. Regrettably, …
Summary 2,5-Dimethoxy-4-nitroamphetamine (DON) is classified as a psychedelic compound within the amphetamine family. Notably, it shares structural similarities with DOM and DOB while exhibiting a close relationship with 2C-N. Identifiers CAS Number 67460-68-8 3D model (JSmol) Interactive imageInteractive image ChEMBL ChEMBL8301 ChemSpider 95083 PubChemCID 105432 UNII 3FIV60666J CompTox Dashboard(EPA) DTXSID00874243 Chemistry Belonging to the category …
Summary 2,5-Dimethoxy-4-methylamphetamine (DOM), also recognized by the acronym STP (representing “Serenity, Tranquility, and Peace”), belongs to the class of psychedelics and substituted amphetamines. Renowned chemist Alexander Shulgin was the first to synthesize this compound, later documenting its properties in his famous book, PiHKAL: A Chemical Love Story. DOM is classified as a Schedule I substance …
Summary 2,5-Dimethoxy-4-isopropylamphetamine also recognized as DOiP and DOiPr, is classified as a psychedelic substance belonging to the phenethylamine and amphetamine chemical groups. The pioneering synthesis of this compound was attributed to Alexander Shulgin and was documented in his book PiHKAL (Phenethylamines I Have Known And Loved). Shulgin noted that DOiPR demonstrated significantly lower potency than …
Summary 2,5-Dimethoxy-4-iodoamphetamine (DOI) is categorized as a psychedelic substance and a form of substituted amphetamine. Unlike other substituted amphetamines, DOI’s primary effects do not primarily manifest as stimulants. The R-(−)-DOI stereoisomer demonstrates more excellent activity with a stereocenter. In neuroscience research, [125I]-R-(−)-DOI is employed as a radioligand, indicating the presence of 5-HT2A serotonin receptors. Comparisons …
Summary 2,5-Dimethoxy-4-ethylamphetamine, also known as DOET, DOE, or Hecate, belongs to the psychedelic realm of drugs within the phenethylamine and amphetamine chemical categories. The compound was initially created by Alexander Shulgin and was documented in his literary work, PiHKAL (Phenethylamines I Have Known And Loved). Identifiers IUPAC name CAS Number 22004-32-6 PubChem CID 27402 DrugBank …
Summary 2,5-Dimethoxy-4-chloroamphetamine (DOC) belongs to the phenethylamine and amphetamine chemical groups and is recognized as a psychedelic substance. Its initial synthesis is attributed to Alexander Shulgin and is documented in detail within his seminal work “PiHKAL” (Phenethylamines I Have Known And Loved). Identifiers IUPAC name CAS Number 123431-31-2 PubChem CID 542036 ChemSpider 472008 UNII 8Y1C6K0PCA …
Summary Dimethoxybromoamphetamine (DOB), alternatively referred to as brolamfetamine (INN), represents a psychedelic substance and substituted amphetamine belonging to the phenethylamine class of compounds. The synthesis of DOB was initially carried out by Alexander Shulgin in 1967, with comprehensive details regarding its production and effects extensively documented in Shulgin’s renowned publication “PiHKAL: A Chemical Love Story.” …
Summary Bromo-DragonFLY, also known as 3C-Bromo-Dragonfly or DOB-Dragonfly, belongs to the phenethylamine family of substances. It functions as a powerful full agonist for the 5-HT2A receptor. Identifiers CAS Number 502759-67-3 3D model (JSmol) Interactive imageInteractive image ChEMBL ChEMBL149024 ChemSpider 8014776 8719838 R 8672089 S PubChemCID 983905710544447 R10496688 S UNII GC9M7R36OI History In 1998, Matthew Parker synthesized Bromo-DragonFLY in the …
